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Selective expression of class-II MHC antigens during hemopoietic differentiation.
Exp Hematol. 1985 Dec; 13(11):1182-7.EH

Abstract

Human multipotential or "mixed" bone marrow colony-forming cells and lineage-restricted colony-forming progenitors have been analyzed by cell sorting (FACS) using a series of monoclonal antibodies. The latter all react with monomorphic class-II MHC glycoprotein determinants but differ in their reactivity or cross-reactivity with products of different loci, i.e., SB (DP), DC (DQ), DR. The results confirm that very few progenitor cells detectably express DC. Anti-DR monoclonals varied in their reactivity with progenitor cells. The majority of progenitors in all lineage categories express determinants that are shared or cross-reactive between DR and SB while fewer progenitors can be shown to bind antibodies specific for DR or SB.

Authors

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Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3864642

Citation

Katz, F E., et al. "Selective Expression of class-II MHC Antigens During Hemopoietic Differentiation." Experimental Hematology, vol. 13, no. 11, 1985, pp. 1182-7.
Katz FE, Davis L, Myers CD, et al. Selective expression of class-II MHC antigens during hemopoietic differentiation. Exp Hematol. 1985;13(11):1182-7.
Katz, F. E., Davis, L., Myers, C. D., & Greaves, M. F. (1985). Selective expression of class-II MHC antigens during hemopoietic differentiation. Experimental Hematology, 13(11), 1182-7.
Katz FE, et al. Selective Expression of class-II MHC Antigens During Hemopoietic Differentiation. Exp Hematol. 1985;13(11):1182-7. PubMed PMID: 3864642.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Selective expression of class-II MHC antigens during hemopoietic differentiation. AU - Katz,F E, AU - Davis,L, AU - Myers,C D, AU - Greaves,M F, PY - 1985/12/1/pubmed PY - 1985/12/1/medline PY - 1985/12/1/entrez SP - 1182 EP - 7 JF - Experimental hematology JO - Exp Hematol VL - 13 IS - 11 N2 - Human multipotential or "mixed" bone marrow colony-forming cells and lineage-restricted colony-forming progenitors have been analyzed by cell sorting (FACS) using a series of monoclonal antibodies. The latter all react with monomorphic class-II MHC glycoprotein determinants but differ in their reactivity or cross-reactivity with products of different loci, i.e., SB (DP), DC (DQ), DR. The results confirm that very few progenitor cells detectably express DC. Anti-DR monoclonals varied in their reactivity with progenitor cells. The majority of progenitors in all lineage categories express determinants that are shared or cross-reactive between DR and SB while fewer progenitors can be shown to bind antibodies specific for DR or SB. SN - 0301-472X UR - https://www.unboundmedicine.com/medline/citation/3864642/Selective_expression_of_class_II_MHC_antigens_during_hemopoietic_differentiation_ L2 - https://medlineplus.gov/stemcells.html DB - PRIME DP - Unbound Medicine ER -