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Epidemiology of multiple sclerosis in US veterans: III. Migration and the risk of MS.
Neurology 1985; 35(5):672-8Neur

Abstract

World War II or Korean Conflict veterans with MS (5,305 in number) and pre-illness-matched controls were compared for residence at birth and entry on active duty (EAD) within three north-south tiers of states in the United States. A strong north-south gradient of MS risk was present. Migrants were defined as those whose birth and EAD tier differed. For white men of World War II, all white men, and all whites, there were highly significant reductions in risk for moves southward from either the north or middle tier, and increases in risk for moves northward from the middle tier. Increases similar in magnitude of middle to north did not attain statistical significance in the few southern-born migrants. For the small groups of black men and white men of Korean service, trends were similar but did not attain significance, whereas for white women, they were of borderline significance. Findings imply an environmental cause for MS, with acquisition years before symptom-onset.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

3873023

Citation

Kurtzke, J F., et al. "Epidemiology of Multiple Sclerosis in US Veterans: III. Migration and the Risk of MS." Neurology, vol. 35, no. 5, 1985, pp. 672-8.
Kurtzke JF, Beebe GW, Norman JE. Epidemiology of multiple sclerosis in US veterans: III. Migration and the risk of MS. Neurology. 1985;35(5):672-8.
Kurtzke, J. F., Beebe, G. W., & Norman, J. E. (1985). Epidemiology of multiple sclerosis in US veterans: III. Migration and the risk of MS. Neurology, 35(5), pp. 672-8.
Kurtzke JF, Beebe GW, Norman JE. Epidemiology of Multiple Sclerosis in US Veterans: III. Migration and the Risk of MS. Neurology. 1985;35(5):672-8. PubMed PMID: 3873023.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epidemiology of multiple sclerosis in US veterans: III. Migration and the risk of MS. AU - Kurtzke,J F, AU - Beebe,G W, AU - Norman,J E,Jr PY - 1985/5/1/pubmed PY - 2001/3/28/medline PY - 1985/5/1/entrez SP - 672 EP - 8 JF - Neurology JO - Neurology VL - 35 IS - 5 N2 - World War II or Korean Conflict veterans with MS (5,305 in number) and pre-illness-matched controls were compared for residence at birth and entry on active duty (EAD) within three north-south tiers of states in the United States. A strong north-south gradient of MS risk was present. Migrants were defined as those whose birth and EAD tier differed. For white men of World War II, all white men, and all whites, there were highly significant reductions in risk for moves southward from either the north or middle tier, and increases in risk for moves northward from the middle tier. Increases similar in magnitude of middle to north did not attain statistical significance in the few southern-born migrants. For the small groups of black men and white men of Korean service, trends were similar but did not attain significance, whereas for white women, they were of borderline significance. Findings imply an environmental cause for MS, with acquisition years before symptom-onset. SN - 0028-3878 UR - https://www.unboundmedicine.com/medline/citation/3873023/Epidemiology_of_multiple_sclerosis_in_US_veterans:_III__Migration_and_the_risk_of_MS_ DB - PRIME DP - Unbound Medicine ER -