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Lupus-like nephritis heralding the definitive manifestation of systemic lupus erythematosus.

Abstract

Four patients presented with the nephrotic syndrome. The histological appearances on renal biopsy were in three characteristic and in one suggestive of lupus nephritis. These patients did not initially have other clinical features of SLE, but three had a positive ANA and one a raised DNA titre. Remission occurred in two patients, in one spontaneously and in another following corticosteroid therapy, but two developed renal failure. During follow-up all developed elevated DNA binding levels and arthralgia or lymphopenia. The ARA classification criteria for lupus were only fulfilled at this late stage.

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Authors

, , , , ,

Source

British journal of rheumatology 24:3 1985 Aug pg 256-62

MeSH

Adult
Antibodies, Antinuclear
Antigen-Antibody Complex
Basement Membrane
Biopsy
Female
Glomerular Mesangium
Glomerulonephritis
Humans
Kidney
Kidney Glomerulus
Lupus Erythematosus, Systemic
Male
Middle Aged
Nephrotic Syndrome
Pregnancy
Pregnancy Complications

Pub Type(s)

Journal Article

Language

eng

PubMed ID

3874672

Citation

Fisher, C, et al. "Lupus-like Nephritis Heralding the Definitive Manifestation of Systemic Lupus Erythematosus." British Journal of Rheumatology, vol. 24, no. 3, 1985, pp. 256-62.
Fisher C, Gibb WR, Cohen SL, et al. Lupus-like nephritis heralding the definitive manifestation of systemic lupus erythematosus. Br J Rheumatol. 1985;24(3):256-62.
Fisher, C., Gibb, W. R., Cohen, S. L., Collins, C. R., Potter, A., & Isenberg, D. A. (1985). Lupus-like nephritis heralding the definitive manifestation of systemic lupus erythematosus. British Journal of Rheumatology, 24(3), pp. 256-62.
Fisher C, et al. Lupus-like Nephritis Heralding the Definitive Manifestation of Systemic Lupus Erythematosus. Br J Rheumatol. 1985;24(3):256-62. PubMed PMID: 3874672.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lupus-like nephritis heralding the definitive manifestation of systemic lupus erythematosus. AU - Fisher,C, AU - Gibb,W R, AU - Cohen,S L, AU - Collins,C R, AU - Potter,A, AU - Isenberg,D A, PY - 1985/8/1/pubmed PY - 1985/8/1/medline PY - 1985/8/1/entrez SP - 256 EP - 62 JF - British journal of rheumatology JO - Br. J. Rheumatol. VL - 24 IS - 3 N2 - Four patients presented with the nephrotic syndrome. The histological appearances on renal biopsy were in three characteristic and in one suggestive of lupus nephritis. These patients did not initially have other clinical features of SLE, but three had a positive ANA and one a raised DNA titre. Remission occurred in two patients, in one spontaneously and in another following corticosteroid therapy, but two developed renal failure. During follow-up all developed elevated DNA binding levels and arthralgia or lymphopenia. The ARA classification criteria for lupus were only fulfilled at this late stage. SN - 0263-7103 UR - https://www.unboundmedicine.com/medline/citation/3874672/Lupus_like_nephritis_heralding_the_definitive_manifestation_of_systemic_lupus_erythematosus_ L2 - http://www.diseaseinfosearch.org/result/4336 DB - PRIME DP - Unbound Medicine ER -