Tags

Type your tag names separated by a space and hit enter

A case of male pseudohermaphroditism with normal androgen receptor binding and 47,XYY karyotype.
Ann Genet. 1985; 28(2):125-9.AG

Abstract

A case of male pseudohermaphroditism with 47,XYY karyotype in blood and cutaneous fibroblasts is described. The plasma testosterone response to HCG stimulation was slightly below the normal range on two occasions suggesting a deficit of gonadal function. A study of the receptors for dihydrotestosterone in fibroblasts of genital and nongenital skin showed a normal concentration of receptors in genital skin; 5-alpha-reductase activity in fibroblasts of the genital skin was low, but the plasma relationship testosterone/dihydrotestosterone under HCG stimulation was normal. The diagnostic possibility of a complete testicular feminization syndrome with normal receptors for dihydrotestosterone is commented on.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

3876063

Citation

Bosch-Banyeras, J M., et al. "A Case of Male Pseudohermaphroditism With Normal Androgen Receptor Binding and 47,XYY Karyotype." Annales De Genetique, vol. 28, no. 2, 1985, pp. 125-9.
Bosch-Banyeras JM, Audi L, Sarret E, et al. A case of male pseudohermaphroditism with normal androgen receptor binding and 47,XYY karyotype. Ann Genet. 1985;28(2):125-9.
Bosch-Banyeras, J. M., Audi, L., Sarret, E., Bau, A., Bosch-Marcet, J., Bernet, M., Iriondo, L., & Cuatrecasas, J. M. (1985). A case of male pseudohermaphroditism with normal androgen receptor binding and 47,XYY karyotype. Annales De Genetique, 28(2), 125-9.
Bosch-Banyeras JM, et al. A Case of Male Pseudohermaphroditism With Normal Androgen Receptor Binding and 47,XYY Karyotype. Ann Genet. 1985;28(2):125-9. PubMed PMID: 3876063.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A case of male pseudohermaphroditism with normal androgen receptor binding and 47,XYY karyotype. AU - Bosch-Banyeras,J M, AU - Audi,L, AU - Sarret,E, AU - Bau,A, AU - Bosch-Marcet,J, AU - Bernet,M, AU - Iriondo,L, AU - Cuatrecasas,J M, PY - 1985/1/1/pubmed PY - 1985/1/1/medline PY - 1985/1/1/entrez SP - 125 EP - 9 JF - Annales de genetique JO - Ann. Genet. VL - 28 IS - 2 N2 - A case of male pseudohermaphroditism with 47,XYY karyotype in blood and cutaneous fibroblasts is described. The plasma testosterone response to HCG stimulation was slightly below the normal range on two occasions suggesting a deficit of gonadal function. A study of the receptors for dihydrotestosterone in fibroblasts of genital and nongenital skin showed a normal concentration of receptors in genital skin; 5-alpha-reductase activity in fibroblasts of the genital skin was low, but the plasma relationship testosterone/dihydrotestosterone under HCG stimulation was normal. The diagnostic possibility of a complete testicular feminization syndrome with normal receptors for dihydrotestosterone is commented on. SN - 0003-3995 UR - https://www.unboundmedicine.com/medline/citation/3876063/A_case_of_male_pseudohermaphroditism_with_normal_androgen_receptor_binding_and_47XYY_karyotype_ L2 - http://www.diseaseinfosearch.org/result/6028 DB - PRIME DP - Unbound Medicine ER -