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Diagnostic efficacy of impedance plethysmography for clinically suspected deep-vein thrombosis. A randomized trial.
Ann Intern Med. 1985 Jan; 102(1):21-8.AIM

Abstract

Impedance plethysmography is an accurate noninvasive method to test for proximal vein thrombosis, but it is insensitive to calf-vein thrombi. We randomly assigned patients on referral with clinically suspected deep-vein thrombosis and normal impedance plethysmographic findings to either serial impedance plethysmography alone or combined impedance plethysmography and leg scanning (which has been shown to be essentially as sensitive as venography) and compared the long-term outcomes. During the initial surveillance, deep-vein thrombosis was detected in 6 of 311 patients (1.9%) tested by serial impedance plethysmography alone and in 30 of 323 patients (9.3%) (most with calf-vein thrombi) tested by the combined approach (p less than 0.001). During long-term follow-up, no patient died from pulmonary embolism; but 6 patients (1.9%; 95% confidence limits, 0.7% to 4.2%) tested by serial impedance plethysmography developed deep-vein thrombosis compared with 7 patients (2.2%; 95% confidence limits, 0.9% to 4.4%) tested by the combined approach. Serial impedance plethysmography used alone is an effective strategy to evaluate such symptomatic patients.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3881068

Citation

Hull, R D., et al. "Diagnostic Efficacy of Impedance Plethysmography for Clinically Suspected Deep-vein Thrombosis. a Randomized Trial." Annals of Internal Medicine, vol. 102, no. 1, 1985, pp. 21-8.
Hull RD, Hirsh J, Carter CJ, et al. Diagnostic efficacy of impedance plethysmography for clinically suspected deep-vein thrombosis. A randomized trial. Ann Intern Med. 1985;102(1):21-8.
Hull, R. D., Hirsh, J., Carter, C. J., Jay, R. M., Ockelford, P. A., Buller, H. R., Turpie, A. G., Powers, P., Kinch, D., & Dodd, P. E. (1985). Diagnostic efficacy of impedance plethysmography for clinically suspected deep-vein thrombosis. A randomized trial. Annals of Internal Medicine, 102(1), 21-8.
Hull RD, et al. Diagnostic Efficacy of Impedance Plethysmography for Clinically Suspected Deep-vein Thrombosis. a Randomized Trial. Ann Intern Med. 1985;102(1):21-8. PubMed PMID: 3881068.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diagnostic efficacy of impedance plethysmography for clinically suspected deep-vein thrombosis. A randomized trial. A1 - Hull,R D, AU - Hirsh,J, AU - Carter,C J, AU - Jay,R M, AU - Ockelford,P A, AU - Buller,H R, AU - Turpie,A G, AU - Powers,P, AU - Kinch,D, AU - Dodd,P E, PY - 1985/1/1/pubmed PY - 1985/1/1/medline PY - 1985/1/1/entrez SP - 21 EP - 8 JF - Annals of internal medicine JO - Ann Intern Med VL - 102 IS - 1 N2 - Impedance plethysmography is an accurate noninvasive method to test for proximal vein thrombosis, but it is insensitive to calf-vein thrombi. We randomly assigned patients on referral with clinically suspected deep-vein thrombosis and normal impedance plethysmographic findings to either serial impedance plethysmography alone or combined impedance plethysmography and leg scanning (which has been shown to be essentially as sensitive as venography) and compared the long-term outcomes. During the initial surveillance, deep-vein thrombosis was detected in 6 of 311 patients (1.9%) tested by serial impedance plethysmography alone and in 30 of 323 patients (9.3%) (most with calf-vein thrombi) tested by the combined approach (p less than 0.001). During long-term follow-up, no patient died from pulmonary embolism; but 6 patients (1.9%; 95% confidence limits, 0.7% to 4.2%) tested by serial impedance plethysmography developed deep-vein thrombosis compared with 7 patients (2.2%; 95% confidence limits, 0.9% to 4.4%) tested by the combined approach. Serial impedance plethysmography used alone is an effective strategy to evaluate such symptomatic patients. SN - 0003-4819 UR - https://www.unboundmedicine.com/medline/citation/3881068/Diagnostic_efficacy_of_impedance_plethysmography_for_clinically_suspected_deep_vein_thrombosis__A_randomized_trial_ L2 - https://www.acpjournals.org/doi/10.7326/0003-4819-102-1-21?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -