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Duodenal microgastrinoma producing the Zollinger-Ellison syndrome.
Arch Pathol Lab Med. 1985 Jan; 109(1):40-2.AP

Abstract

A 1.5-mm gastrinoma of the duodenal wall was discovered during dissection of a duodenal ulcer in a patient in whom the Zollinger-Ellison (ZE) syndrome was later suspected due to gross autopsy findings. Multiple duodenal ulcers and gastric rugal hypertrophy were noted, and hyperplasia of the parietal cells associated with a duodenal gastrinoma was confirmed by immunohistochemical studies. In many cases of ZE syndrome, a primary neoplasm cannot be localized by angiography, computed tomography, ultrasound, or palpation at exploratory laparotomy. If a neoplasm cannot be identified, many cases will be attributed to islet cell hyperplasia, or antropyloric gastrin cell (G cell) hyperplasia. This case confirms that the primary neoplasm may be grossly undetectable and still produce the clinicomorphologic manifestations of this syndrome.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

3882073

Citation

Vesoulis, Z, and R E. Petras. "Duodenal Microgastrinoma Producing the Zollinger-Ellison Syndrome." Archives of Pathology & Laboratory Medicine, vol. 109, no. 1, 1985, pp. 40-2.
Vesoulis Z, Petras RE. Duodenal microgastrinoma producing the Zollinger-Ellison syndrome. Arch Pathol Lab Med. 1985;109(1):40-2.
Vesoulis, Z., & Petras, R. E. (1985). Duodenal microgastrinoma producing the Zollinger-Ellison syndrome. Archives of Pathology & Laboratory Medicine, 109(1), 40-2.
Vesoulis Z, Petras RE. Duodenal Microgastrinoma Producing the Zollinger-Ellison Syndrome. Arch Pathol Lab Med. 1985;109(1):40-2. PubMed PMID: 3882073.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Duodenal microgastrinoma producing the Zollinger-Ellison syndrome. AU - Vesoulis,Z, AU - Petras,R E, PY - 1985/1/1/pubmed PY - 1985/1/1/medline PY - 1985/1/1/entrez SP - 40 EP - 2 JF - Archives of pathology & laboratory medicine JO - Arch Pathol Lab Med VL - 109 IS - 1 N2 - A 1.5-mm gastrinoma of the duodenal wall was discovered during dissection of a duodenal ulcer in a patient in whom the Zollinger-Ellison (ZE) syndrome was later suspected due to gross autopsy findings. Multiple duodenal ulcers and gastric rugal hypertrophy were noted, and hyperplasia of the parietal cells associated with a duodenal gastrinoma was confirmed by immunohistochemical studies. In many cases of ZE syndrome, a primary neoplasm cannot be localized by angiography, computed tomography, ultrasound, or palpation at exploratory laparotomy. If a neoplasm cannot be identified, many cases will be attributed to islet cell hyperplasia, or antropyloric gastrin cell (G cell) hyperplasia. This case confirms that the primary neoplasm may be grossly undetectable and still produce the clinicomorphologic manifestations of this syndrome. SN - 0003-9985 UR - https://www.unboundmedicine.com/medline/citation/3882073/Duodenal_microgastrinoma_producing_the_Zollinger_Ellison_syndrome_ L2 - http://www.diseaseinfosearch.org/result/7600 DB - PRIME DP - Unbound Medicine ER -