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A yeast-derived antigen from Paracoccidioides brasiliensis useful for serologic testing.
Sabouraudia. 1985 Feb; 23(1):23-9.S

Abstract

Antigens prepared from P. brasiliensis yeast cells subjected to ultrasonic treatment proved reliable in the serological diagnosis of paracoccidioidomycosis. Detection of antibodies was possible in over 90% from paracoccidioidomycosis patients in tests with agar gel immunodiffusion and counterimmunoelectrophoresis. Specificity was high and only histoplasmosis sera produced cross reactions, albeit at a lower frequency (10%). The new antigens compared favorably to the standard yeast culture filtrate antigen used in the past and they have the advantage of being reproducible. Proper control of proteolysis is required if activity is to be preserved.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3922069

Citation

Restrepo, A, et al. "A Yeast-derived Antigen From Paracoccidioides Brasiliensis Useful for Serologic Testing." Sabouraudia, vol. 23, no. 1, 1985, pp. 23-9.
Restrepo A, Cano LE, Ochoa MT. A yeast-derived antigen from Paracoccidioides brasiliensis useful for serologic testing. Sabouraudia. 1985;23(1):23-9.
Restrepo, A., Cano, L. E., & Ochoa, M. T. (1985). A yeast-derived antigen from Paracoccidioides brasiliensis useful for serologic testing. Sabouraudia, 23(1), 23-9.
Restrepo A, Cano LE, Ochoa MT. A Yeast-derived Antigen From Paracoccidioides Brasiliensis Useful for Serologic Testing. Sabouraudia. 1985;23(1):23-9. PubMed PMID: 3922069.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A yeast-derived antigen from Paracoccidioides brasiliensis useful for serologic testing. AU - Restrepo,A, AU - Cano,L E, AU - Ochoa,M T, PY - 1985/2/1/pubmed PY - 1985/2/1/medline PY - 1985/2/1/entrez SP - 23 EP - 9 JF - Sabouraudia JO - Sabouraudia VL - 23 IS - 1 N2 - Antigens prepared from P. brasiliensis yeast cells subjected to ultrasonic treatment proved reliable in the serological diagnosis of paracoccidioidomycosis. Detection of antibodies was possible in over 90% from paracoccidioidomycosis patients in tests with agar gel immunodiffusion and counterimmunoelectrophoresis. Specificity was high and only histoplasmosis sera produced cross reactions, albeit at a lower frequency (10%). The new antigens compared favorably to the standard yeast culture filtrate antigen used in the past and they have the advantage of being reproducible. Proper control of proteolysis is required if activity is to be preserved. SN - 0036-2174 UR - https://www.unboundmedicine.com/medline/citation/3922069/A_yeast_derived_antigen_from_Paracoccidioides_brasiliensis_useful_for_serologic_testing_ L2 - https://medlineplus.gov/molds.html DB - PRIME DP - Unbound Medicine ER -