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Light damage in the developing retina of the albino rat: an electroretinographic study.
Invest Ophthalmol Vis Sci 1986; 27(2):164-7IO

Abstract

The albino rat retina is severely damaged by exposure to bright light. The degree of damage depends upon the intensity of the exposure and its duration. In the present study, electroretinographic (ERG) responses were measured in rats exposed at different ages during the period of retinal development to 24 hr of bright light and then transferred to darkness for about 2 months. The ERG data indicated that if the bright-light exposure was done prior to 20 days of age, the retina was resistant to the light damage, and the dark-adapted ERG responses measured later were normal. In rats older than 20 days, light damage increased with age until, in rats exposed to light at age 30 days, the ERG was unrecordable. Further experiments showed that light exposure did damage the 15-day-old rat retina; however, complete recovery was attained within 15 days postexposure.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3943942

Citation

Malik, S, et al. "Light Damage in the Developing Retina of the Albino Rat: an Electroretinographic Study." Investigative Ophthalmology & Visual Science, vol. 27, no. 2, 1986, pp. 164-7.
Malik S, Cohen D, Meyer E, et al. Light damage in the developing retina of the albino rat: an electroretinographic study. Invest Ophthalmol Vis Sci. 1986;27(2):164-7.
Malik, S., Cohen, D., Meyer, E., & Perlman, I. (1986). Light damage in the developing retina of the albino rat: an electroretinographic study. Investigative Ophthalmology & Visual Science, 27(2), pp. 164-7.
Malik S, et al. Light Damage in the Developing Retina of the Albino Rat: an Electroretinographic Study. Invest Ophthalmol Vis Sci. 1986;27(2):164-7. PubMed PMID: 3943942.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Light damage in the developing retina of the albino rat: an electroretinographic study. AU - Malik,S, AU - Cohen,D, AU - Meyer,E, AU - Perlman,I, PY - 1986/2/1/pubmed PY - 1986/2/1/medline PY - 1986/2/1/entrez SP - 164 EP - 7 JF - Investigative ophthalmology & visual science JO - Invest. Ophthalmol. Vis. Sci. VL - 27 IS - 2 N2 - The albino rat retina is severely damaged by exposure to bright light. The degree of damage depends upon the intensity of the exposure and its duration. In the present study, electroretinographic (ERG) responses were measured in rats exposed at different ages during the period of retinal development to 24 hr of bright light and then transferred to darkness for about 2 months. The ERG data indicated that if the bright-light exposure was done prior to 20 days of age, the retina was resistant to the light damage, and the dark-adapted ERG responses measured later were normal. In rats older than 20 days, light damage increased with age until, in rats exposed to light at age 30 days, the ERG was unrecordable. Further experiments showed that light exposure did damage the 15-day-old rat retina; however, complete recovery was attained within 15 days postexposure. SN - 0146-0404 UR - https://www.unboundmedicine.com/medline/citation/3943942/Light_damage_in_the_developing_retina_of_the_albino_rat:_an_electroretinographic_study_ L2 - https://iovs.arvojournals.org/article.aspx?volume=27&issue=2&page=164 DB - PRIME DP - Unbound Medicine ER -