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Pseudoephedrine-induced hypertensive emergency: treatment with labetalol.
Am J Emerg Med. 1986 Mar; 4(2):141-2.AJ

Abstract

The case of a young man in hypertensive emergency following the ingestion of 840 mg of pseudoephedrine is reported. The hypertension, which peaked at 200/160 mm Hg and was associated with severe headache and diaphoresis, responded expeditiously to two initial intravenous doses of labetalol. No rebound was observed following the administration of an additional dose in the intensive care unit, after which an uneventful one-day hospitalization ensued. The toxicity of pseudoephedrine is briefly reviewed along with the pharmacology and use of labetalol. On the basis of previous experimental studies and the present report, labetalol is suggested as a promising agent in the treatment of hyperadrenergic-induced hypertensive emergencies.

Authors

Mariani PJ
No affiliation info available

MeSH

AdultCyproheptadineEphedrineHumansHypertensionInfusions, ParenteralLabetalolMaleSubstance-Related Disorders

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

3947442

Citation

Mariani, P J.. "Pseudoephedrine-induced Hypertensive Emergency: Treatment With Labetalol." The American Journal of Emergency Medicine, vol. 4, no. 2, 1986, pp. 141-2.
Mariani PJ. Pseudoephedrine-induced hypertensive emergency: treatment with labetalol. Am J Emerg Med. 1986;4(2):141-2.
Mariani, P. J. (1986). Pseudoephedrine-induced hypertensive emergency: treatment with labetalol. The American Journal of Emergency Medicine, 4(2), 141-2.
Mariani PJ. Pseudoephedrine-induced Hypertensive Emergency: Treatment With Labetalol. Am J Emerg Med. 1986;4(2):141-2. PubMed PMID: 3947442.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pseudoephedrine-induced hypertensive emergency: treatment with labetalol. A1 - Mariani,P J, PY - 1986/3/1/pubmed PY - 1986/3/1/medline PY - 1986/3/1/entrez SP - 141 EP - 2 JF - The American journal of emergency medicine JO - Am J Emerg Med VL - 4 IS - 2 N2 - The case of a young man in hypertensive emergency following the ingestion of 840 mg of pseudoephedrine is reported. The hypertension, which peaked at 200/160 mm Hg and was associated with severe headache and diaphoresis, responded expeditiously to two initial intravenous doses of labetalol. No rebound was observed following the administration of an additional dose in the intensive care unit, after which an uneventful one-day hospitalization ensued. The toxicity of pseudoephedrine is briefly reviewed along with the pharmacology and use of labetalol. On the basis of previous experimental studies and the present report, labetalol is suggested as a promising agent in the treatment of hyperadrenergic-induced hypertensive emergencies. SN - 0735-6757 UR - https://www.unboundmedicine.com/medline/citation/3947442/Pseudoephedrine_induced_hypertensive_emergency:_treatment_with_labetalol_ DB - PRIME DP - Unbound Medicine ER -