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Insulin treatment and state of control before, during, and after connection to a glucose controlled insulin infusion system (Biostator).

Abstract

Nine insulin-dependent, juvenile-onset diabetics were treated for more than twenty four hours with an artificial beta cell (Biostator). Using the amounts and profile of the insulin delivered by the machine as a guide for subsequent subcutaneous therapy, a better state of control was obtained. However, with the algorithm constants used, we found the Biostator to deliver more insulin (average 36%) than needed for subcutaneous therapy. Repeated oral glucose tolerance tests show that constants used in the algorithms might be optimized.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

395069

Citation

Christiansen, J S., et al. "Insulin Treatment and State of Control Before, During, and After Connection to a Glucose Controlled Insulin Infusion System (Biostator)." Hormone and Metabolic Research. Supplement Series, 1979, pp. 131-4.
Christiansen JS, Svendsen PA, Deckert T. Insulin treatment and state of control before, during, and after connection to a glucose controlled insulin infusion system (Biostator). Horm Metab Res Suppl. 1979.
Christiansen, J. S., Svendsen, P. A., & Deckert, T. (1979). Insulin treatment and state of control before, during, and after connection to a glucose controlled insulin infusion system (Biostator). Hormone and Metabolic Research. Supplement Series, (8), 131-4.
Christiansen JS, Svendsen PA, Deckert T. Insulin Treatment and State of Control Before, During, and After Connection to a Glucose Controlled Insulin Infusion System (Biostator). Horm Metab Res Suppl. 1979;(8)131-4. PubMed PMID: 395069.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Insulin treatment and state of control before, during, and after connection to a glucose controlled insulin infusion system (Biostator). AU - Christiansen,J S, AU - Svendsen,P A, AU - Deckert,T, PY - 1979/1/1/pubmed PY - 1979/1/1/medline PY - 1979/1/1/entrez SP - 131 EP - 4 JF - Hormone and metabolic research. Supplement series JO - Horm Metab Res Suppl IS - 8 N2 - Nine insulin-dependent, juvenile-onset diabetics were treated for more than twenty four hours with an artificial beta cell (Biostator). Using the amounts and profile of the insulin delivered by the machine as a guide for subsequent subcutaneous therapy, a better state of control was obtained. However, with the algorithm constants used, we found the Biostator to deliver more insulin (average 36%) than needed for subcutaneous therapy. Repeated oral glucose tolerance tests show that constants used in the algorithms might be optimized. SN - 0170-5903 UR - https://www.unboundmedicine.com/medline/citation/395069/Insulin_treatment_and_state_of_control_before_during_and_after_connection_to_a_glucose_controlled_insulin_infusion_system__Biostator__ L2 - https://medlineplus.gov/diabetesmedicines.html DB - PRIME DP - Unbound Medicine ER -