TY - JOUR T1 - Use of an artificial beta cell in surgery. AU - Horwitz,D L, AU - Schwartz,S S, PY - 1979/1/1/pubmed PY - 1979/1/1/medline PY - 1979/1/1/entrez SP - 156 EP - 8 JF - Hormone and metabolic research. Supplement series JO - Horm Metab Res Suppl IS - 8 N2 - Using a Biostator glucose-controlled insulin infusion system to monitor blood glucose during surgery, we have shown that both nondiabetic and diabetic patients have a tendency towards hyperglycemia during surgery. This appears to be due to suppression of endogenous insulin secretion as measured by serum C-peptide levels. Some diabetic patients maintained relatively normal glucose values during surgery when infused with saline alone and not given glucose or insulin, but 2 of 5 were not well controlled by this means. Hyperglycemia in both diabetic and non-diabetic patients was related to the rate of infusion of exogenous glucose. The biostator glucose-controlled insulin infusion system could be used in feedback mode as an apparently safe and effective means of controlling blood glucose during surgery on diabetic patients. SN - 0170-5903 UR - https://www.unboundmedicine.com/medline/citation/395072/Use_of_an_artificial_beta_cell_in_surgery_ L2 - https://medlineplus.gov/surgery.html DB - PRIME DP - Unbound Medicine ER -