TY - JOUR T1 - Closed-loop system in evaluation of insulin infusion rates for an open-loop system. AU - Kølendorf,K, AU - Christiansen,J S, AU - Svendsen,P A, AU - Bojsen,J, PY - 1979/1/1/pubmed PY - 1979/1/1/medline PY - 1979/1/1/entrez SP - 205 EP - 6 JF - Hormone and metabolic research. Supplement series JO - Horm Metab Res Suppl IS - 8 N2 - The daily insulin requirements as calculated with a closed-loop system (Biostator), were used for insulin infusion with a portable, miniaturized pump in 6 juvenile-onset, insulin-requiring diabetics. Three diabetics were given insulin in a manner like that of the Biostator, e.g., maximal insulin infusion about 1 hour after start of meals. The MBG was 8.7 +/- 3.9 (SD) mmol/l. Three other diabetics had insulin in a fixed profile with peaks beginning simultaneously with meals. MBG of these patients was 4.4 +/- 1.9 mmol/l. Knowing the daily insulin dosage as calculated from the Biostator, normal blood glucose levels can be achieved with a fixed profile of insulin given by a portable pump. SN - 0170-5903 UR - https://www.unboundmedicine.com/medline/citation/395082/Closed_loop_system_in_evaluation_of_insulin_infusion_rates_for_an_open_loop_system_ DB - PRIME DP - Unbound Medicine ER -