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Closed-loop system in evaluation of insulin infusion rates for an open-loop system.

Abstract

The daily insulin requirements as calculated with a closed-loop system (Biostator), were used for insulin infusion with a portable, miniaturized pump in 6 juvenile-onset, insulin-requiring diabetics. Three diabetics were given insulin in a manner like that of the Biostator, e.g., maximal insulin infusion about 1 hour after start of meals. The MBG was 8.7 +/- 3.9 (SD) mmol/l. Three other diabetics had insulin in a fixed profile with peaks beginning simultaneously with meals. MBG of these patients was 4.4 +/- 1.9 mmol/l. Knowing the daily insulin dosage as calculated from the Biostator, normal blood glucose levels can be achieved with a fixed profile of insulin given by a portable pump.

Authors

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Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

395082

Citation

Kølendorf, K, et al. "Closed-loop System in Evaluation of Insulin Infusion Rates for an Open-loop System." Hormone and Metabolic Research. Supplement Series, 1979, pp. 205-6.
Kølendorf K, Christiansen JS, Svendsen PA, et al. Closed-loop system in evaluation of insulin infusion rates for an open-loop system. Horm Metab Res Suppl. 1979.
Kølendorf, K., Christiansen, J. S., Svendsen, P. A., & Bojsen, J. (1979). Closed-loop system in evaluation of insulin infusion rates for an open-loop system. Hormone and Metabolic Research. Supplement Series, (8), 205-6.
Kølendorf K, et al. Closed-loop System in Evaluation of Insulin Infusion Rates for an Open-loop System. Horm Metab Res Suppl. 1979;(8)205-6. PubMed PMID: 395082.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Closed-loop system in evaluation of insulin infusion rates for an open-loop system. AU - Kølendorf,K, AU - Christiansen,J S, AU - Svendsen,P A, AU - Bojsen,J, PY - 1979/1/1/pubmed PY - 1979/1/1/medline PY - 1979/1/1/entrez SP - 205 EP - 6 JF - Hormone and metabolic research. Supplement series JO - Horm Metab Res Suppl IS - 8 N2 - The daily insulin requirements as calculated with a closed-loop system (Biostator), were used for insulin infusion with a portable, miniaturized pump in 6 juvenile-onset, insulin-requiring diabetics. Three diabetics were given insulin in a manner like that of the Biostator, e.g., maximal insulin infusion about 1 hour after start of meals. The MBG was 8.7 +/- 3.9 (SD) mmol/l. Three other diabetics had insulin in a fixed profile with peaks beginning simultaneously with meals. MBG of these patients was 4.4 +/- 1.9 mmol/l. Knowing the daily insulin dosage as calculated from the Biostator, normal blood glucose levels can be achieved with a fixed profile of insulin given by a portable pump. SN - 0170-5903 UR - https://www.unboundmedicine.com/medline/citation/395082/Closed_loop_system_in_evaluation_of_insulin_infusion_rates_for_an_open_loop_system_ L2 - https://medlineplus.gov/diabetesmedicines.html DB - PRIME DP - Unbound Medicine ER -