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[Indications for using trental in the initial manifestations of inadequate blood supply to the brain].

Abstract

The action of trental was studied in 125 patients with initial manifestations of cerebral circulation insufficiency (CCI) secondary to vasomotor dystonia or atherosclerosis. Trental was used in the form of tablets (100 mg 3 times daily) for 60 days. To assess the therapeutic effect of trental, the authors analyzed the time-course of subjective manifestations, parameters of echopulsography of cerebral vessels and biomicroscopy of the conjunctiva, and the data of the total blood count and the rheological properties of the blood. In patients with initial manifestations of CCI trental decreased the cerebral vascular resistance and improved the venous outflow, reduced platelet adhesive and aggregation properties and diminished blood viscosity. It also elevated the spontaneous fibrinolytic activity of the blood. The advisability of selective administration of the drug for treating initial manifestations of CCI was confirmed.

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

rus

PubMed ID

3953193

Citation

Eninia, G I., et al. "[Indications for Using Trental in the Initial Manifestations of Inadequate Blood Supply to the Brain]." Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952), vol. 86, no. 1, 1986, pp. 50-2.
Eninia GI, Egere DA, Robule VKh, et al. [Indications for using trental in the initial manifestations of inadequate blood supply to the brain]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1986;86(1):50-2.
Eninia, G. I., Egere, D. A., Robule, V. K. h., & Maĭore, I. K. h. (1986). [Indications for using trental in the initial manifestations of inadequate blood supply to the brain]. Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952), 86(1), pp. 50-2.
Eninia GI, et al. [Indications for Using Trental in the Initial Manifestations of Inadequate Blood Supply to the Brain]. Zh Nevropatol Psikhiatr Im S S Korsakova. 1986;86(1):50-2. PubMed PMID: 3953193.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Indications for using trental in the initial manifestations of inadequate blood supply to the brain]. AU - Eninia,G I, AU - Egere,D A, AU - Robule,V Kh, AU - Maĭore,I Kh, PY - 1986/1/1/pubmed PY - 1986/1/1/medline PY - 1986/1/1/entrez SP - 50 EP - 2 JF - Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) JO - Zh Nevropatol Psikhiatr Im S S Korsakova VL - 86 IS - 1 N2 - The action of trental was studied in 125 patients with initial manifestations of cerebral circulation insufficiency (CCI) secondary to vasomotor dystonia or atherosclerosis. Trental was used in the form of tablets (100 mg 3 times daily) for 60 days. To assess the therapeutic effect of trental, the authors analyzed the time-course of subjective manifestations, parameters of echopulsography of cerebral vessels and biomicroscopy of the conjunctiva, and the data of the total blood count and the rheological properties of the blood. In patients with initial manifestations of CCI trental decreased the cerebral vascular resistance and improved the venous outflow, reduced platelet adhesive and aggregation properties and diminished blood viscosity. It also elevated the spontaneous fibrinolytic activity of the blood. The advisability of selective administration of the drug for treating initial manifestations of CCI was confirmed. SN - 0044-4588 UR - https://www.unboundmedicine.com/medline/citation/3953193/[Indications_for_using_trental_in_the_initial_manifestations_of_inadequate_blood_supply_to_the_brain]_ DB - PRIME DP - Unbound Medicine ER -