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Absorptive hyperoxaluria: a new clinical entity--successful treatment with hydrochlorothiazide.
Clin Invest Med. 1986; 9(1):44-50.CI

Abstract

This report describes studies performed over an 11 year period in a 13 year old girl with hyperoxaluria and calcium oxalate nephrolithiasis who did not have primary hyperoxaluria or any of the recognized causes of secondary hyperoxaluria. The patient also had increased urinary excretion of calcium and magnesium and hyperabsorption of dietary calcium and magnesium. It is suggested that the hyperoxaluria resulted from hyperabsorption of dietary oxalate secondary to hyperabsorption of dietary calcium. Hyperabsorption of dietary magnesium and increased urinary magnesium excretion have not previously been reported in this context. Stone formation ceased and urinary oxalate excretion gradually fell to normal during long term thiazide therapy but hyperoxaluria recurred when orthophosphate therapy was substituted for the hydrochlorothiazide. This is the first report of normalization of urine oxalate excretion during thiazide therapy in a patient with frank hyperoxaluria.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3955921

Citation

Yendt, E R., and M Cohanim. "Absorptive Hyperoxaluria: a New Clinical Entity--successful Treatment With Hydrochlorothiazide." Clinical and Investigative Medicine. Medecine Clinique Et Experimentale, vol. 9, no. 1, 1986, pp. 44-50.
Yendt ER, Cohanim M. Absorptive hyperoxaluria: a new clinical entity--successful treatment with hydrochlorothiazide. Clin Invest Med. 1986;9(1):44-50.
Yendt, E. R., & Cohanim, M. (1986). Absorptive hyperoxaluria: a new clinical entity--successful treatment with hydrochlorothiazide. Clinical and Investigative Medicine. Medecine Clinique Et Experimentale, 9(1), 44-50.
Yendt ER, Cohanim M. Absorptive Hyperoxaluria: a New Clinical Entity--successful Treatment With Hydrochlorothiazide. Clin Invest Med. 1986;9(1):44-50. PubMed PMID: 3955921.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Absorptive hyperoxaluria: a new clinical entity--successful treatment with hydrochlorothiazide. AU - Yendt,E R, AU - Cohanim,M, PY - 1986/1/1/pubmed PY - 1986/1/1/medline PY - 1986/1/1/entrez SP - 44 EP - 50 JF - Clinical and investigative medicine. Medecine clinique et experimentale JO - Clin Invest Med VL - 9 IS - 1 N2 - This report describes studies performed over an 11 year period in a 13 year old girl with hyperoxaluria and calcium oxalate nephrolithiasis who did not have primary hyperoxaluria or any of the recognized causes of secondary hyperoxaluria. The patient also had increased urinary excretion of calcium and magnesium and hyperabsorption of dietary calcium and magnesium. It is suggested that the hyperoxaluria resulted from hyperabsorption of dietary oxalate secondary to hyperabsorption of dietary calcium. Hyperabsorption of dietary magnesium and increased urinary magnesium excretion have not previously been reported in this context. Stone formation ceased and urinary oxalate excretion gradually fell to normal during long term thiazide therapy but hyperoxaluria recurred when orthophosphate therapy was substituted for the hydrochlorothiazide. This is the first report of normalization of urine oxalate excretion during thiazide therapy in a patient with frank hyperoxaluria. SN - 0147-958X UR - https://www.unboundmedicine.com/medline/citation/3955921/Absorptive_hyperoxaluria:_a_new_clinical_entity__successful_treatment_with_hydrochlorothiazide_ L2 - http://www.diseaseinfosearch.org/result/3587 DB - PRIME DP - Unbound Medicine ER -