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Occurrence of elevated protoporphyrin levels in relation to lead burden in infants.
Environ Res. 1986 Apr; 39(2):253-7.ER

Abstract

Simultaneous blood lead (PbB), erythrocyte protoporphyrin (EP), and hematocrit measurements were made semiannually in 232 normal infants from 6 to 24 months of age. The PbB averaged 7 (SD = 5) and ranged from 0 to 64 micrograms/dl. The incidence of elevated EP, a marker for deranged heme synthesis, was unrelated to PbB at levels below 15 micrograms/dl but was fourfold greater among the infants with PbB above 15 micrograms/dl. This relationship persisted even after eliminating the 31 (4%) anemic (hematocrit less than 33%) samples. The confounding effects of iron deficiency are discussed.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

3956457

Citation

Rabinowitz, M B., et al. "Occurrence of Elevated Protoporphyrin Levels in Relation to Lead Burden in Infants." Environmental Research, vol. 39, no. 2, 1986, pp. 253-7.
Rabinowitz MB, Leviton A, Needleman HL. Occurrence of elevated protoporphyrin levels in relation to lead burden in infants. Environ Res. 1986;39(2):253-7.
Rabinowitz, M. B., Leviton, A., & Needleman, H. L. (1986). Occurrence of elevated protoporphyrin levels in relation to lead burden in infants. Environmental Research, 39(2), 253-7.
Rabinowitz MB, Leviton A, Needleman HL. Occurrence of Elevated Protoporphyrin Levels in Relation to Lead Burden in Infants. Environ Res. 1986;39(2):253-7. PubMed PMID: 3956457.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Occurrence of elevated protoporphyrin levels in relation to lead burden in infants. AU - Rabinowitz,M B, AU - Leviton,A, AU - Needleman,H L, PY - 1986/4/1/pubmed PY - 1986/4/1/medline PY - 1986/4/1/entrez SP - 253 EP - 7 JF - Environmental research JO - Environ Res VL - 39 IS - 2 N2 - Simultaneous blood lead (PbB), erythrocyte protoporphyrin (EP), and hematocrit measurements were made semiannually in 232 normal infants from 6 to 24 months of age. The PbB averaged 7 (SD = 5) and ranged from 0 to 64 micrograms/dl. The incidence of elevated EP, a marker for deranged heme synthesis, was unrelated to PbB at levels below 15 micrograms/dl but was fourfold greater among the infants with PbB above 15 micrograms/dl. This relationship persisted even after eliminating the 31 (4%) anemic (hematocrit less than 33%) samples. The confounding effects of iron deficiency are discussed. SN - 0013-9351 UR - https://www.unboundmedicine.com/medline/citation/3956457/Occurrence_of_elevated_protoporphyrin_levels_in_relation_to_lead_burden_in_infants_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0013-9351(86)80051-2 DB - PRIME DP - Unbound Medicine ER -