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[Effect of a course of pentoxifylline (trental) treatment on microcirculatory and central hemodynamic functions in chronic ischemic heart disease patients].
Ter Arkh 1985; 57(1):43-6TA

Abstract

The author studied the effect of trental therapy lasting one month on the functions of the microcirculation and central hemodynamics in 45 patients with chronic coronary heart disease (CHD). It was established that as regards the clinical response to the treatment all the patients could be distributed into 2 groups: responsive and refractory to therapy. In patients who responded to the treatment (36 persons), the rate of the microlymph flow and capillary permeability substantially increased. The increase in capillary permeability led to a lowering in the CPV and BCV, which in turn gave rise to a reduction in the parameters of the cardiac output. There were no changes on the whole in the microhemodynamics. In patients refractory to therapy, trental treatment did not bring about any changes in the central hemodynamics, microhemodynamics or lymphodynamics. Capillary permeability dropped with a high degree of significance. The data obtained point to the necessity of a differential approach to the treatment of CHD patients with trental.

Authors

No affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

rus

PubMed ID

3983842

Citation

Atroshchenko, E S.. "[Effect of a Course of Pentoxifylline (trental) Treatment On Microcirculatory and Central Hemodynamic Functions in Chronic Ischemic Heart Disease Patients]." Terapevticheskii Arkhiv, vol. 57, no. 1, 1985, pp. 43-6.
Atroshchenko ES. [Effect of a course of pentoxifylline (trental) treatment on microcirculatory and central hemodynamic functions in chronic ischemic heart disease patients]. Ter Arkh. 1985;57(1):43-6.
Atroshchenko, E. S. (1985). [Effect of a course of pentoxifylline (trental) treatment on microcirculatory and central hemodynamic functions in chronic ischemic heart disease patients]. Terapevticheskii Arkhiv, 57(1), pp. 43-6.
Atroshchenko ES. [Effect of a Course of Pentoxifylline (trental) Treatment On Microcirculatory and Central Hemodynamic Functions in Chronic Ischemic Heart Disease Patients]. Ter Arkh. 1985;57(1):43-6. PubMed PMID: 3983842.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Effect of a course of pentoxifylline (trental) treatment on microcirculatory and central hemodynamic functions in chronic ischemic heart disease patients]. A1 - Atroshchenko,E S, PY - 1985/1/1/pubmed PY - 1985/1/1/medline PY - 1985/1/1/entrez SP - 43 EP - 6 JF - Terapevticheskii arkhiv JO - Ter. Arkh. VL - 57 IS - 1 N2 - The author studied the effect of trental therapy lasting one month on the functions of the microcirculation and central hemodynamics in 45 patients with chronic coronary heart disease (CHD). It was established that as regards the clinical response to the treatment all the patients could be distributed into 2 groups: responsive and refractory to therapy. In patients who responded to the treatment (36 persons), the rate of the microlymph flow and capillary permeability substantially increased. The increase in capillary permeability led to a lowering in the CPV and BCV, which in turn gave rise to a reduction in the parameters of the cardiac output. There were no changes on the whole in the microhemodynamics. In patients refractory to therapy, trental treatment did not bring about any changes in the central hemodynamics, microhemodynamics or lymphodynamics. Capillary permeability dropped with a high degree of significance. The data obtained point to the necessity of a differential approach to the treatment of CHD patients with trental. SN - 0040-3660 UR - https://www.unboundmedicine.com/medline/citation/3983842/[Effect_of_a_course_of_pentoxifylline__trental__treatment_on_microcirculatory_and_central_hemodynamic_functions_in_chronic_ischemic_heart_disease_patients]_ L2 - http://www.diseaseinfosearch.org/result/130 DB - PRIME DP - Unbound Medicine ER -