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[Gastric emptying of a solid-liquid meal in normal subjects: validity of the labeling (99mTc) of chicken liver by a multipuncture technic].
Gastroenterol Clin Biol. 1985 Apr; 9(4):342-7.GC

Abstract

For gastric emptying studies of a solid-liquid meal by the scintigraphic method, a valid isotope labeling method for each phase of the meal must be obtained. The aim of this study was to validate a simple chicken liver labeling method in normal subjects by multipuncture technic with 99mtechnetium. Labeling according to Meyer's method was chosen as a reference. Simultaneously, a study of the quality of liquid phase labeling by 111indium was done. The labeling process quality for each phase of the meal was assessed: a) in vitro, after incubation of the meal with human gastric juice (n = 12); b) in vivo, after meal ingestion and sequential collection of gastric contents by aspiration (n = 4). Furthermore, in 8 healthy volunteers, gastric emptying curves of the solid and liquid phases of the meal were determined scintigraphically and compared. Our results showed: a) for the solid phase: a good specificity of the marker, which was assessed in vitro and in vivo, after liver labeling with multipuncture technique (89 p. 100 and 92 p. 100 after 180 min, respectively); b) for the liquid phase: a good specificity of the marker in vitro and a poor specificity in vivo (82 p. 100 and 27 p. 100 after 180 min, respectively); c) similar half-gastric emptying times and cumulative percentages for the solid and liquid phases with both liver labeling methods. In conclusion, the multipuncture technique for chicken liver labeling may be used for gastric emptying studies in humans.

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

fre

PubMed ID

3996817

Citation

Hostein, J, et al. "[Gastric Emptying of a Solid-liquid Meal in Normal Subjects: Validity of the Labeling (99mTc) of Chicken Liver By a Multipuncture Technic]." Gastroenterologie Clinique Et Biologique, vol. 9, no. 4, 1985, pp. 342-7.
Hostein J, Capony P, Busquet G, et al. [Gastric emptying of a solid-liquid meal in normal subjects: validity of the labeling (99mTc) of chicken liver by a multipuncture technic]. Gastroenterol Clin Biol. 1985;9(4):342-7.
Hostein, J., Capony, P., Busquet, G., Bost, R., & Fournet, J. (1985). [Gastric emptying of a solid-liquid meal in normal subjects: validity of the labeling (99mTc) of chicken liver by a multipuncture technic]. Gastroenterologie Clinique Et Biologique, 9(4), 342-7.
Hostein J, et al. [Gastric Emptying of a Solid-liquid Meal in Normal Subjects: Validity of the Labeling (99mTc) of Chicken Liver By a Multipuncture Technic]. Gastroenterol Clin Biol. 1985;9(4):342-7. PubMed PMID: 3996817.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Gastric emptying of a solid-liquid meal in normal subjects: validity of the labeling (99mTc) of chicken liver by a multipuncture technic]. AU - Hostein,J, AU - Capony,P, AU - Busquet,G, AU - Bost,R, AU - Fournet,J, PY - 1985/4/1/pubmed PY - 1985/4/1/medline PY - 1985/4/1/entrez SP - 342 EP - 7 JF - Gastroenterologie clinique et biologique JO - Gastroenterol Clin Biol VL - 9 IS - 4 N2 - For gastric emptying studies of a solid-liquid meal by the scintigraphic method, a valid isotope labeling method for each phase of the meal must be obtained. The aim of this study was to validate a simple chicken liver labeling method in normal subjects by multipuncture technic with 99mtechnetium. Labeling according to Meyer's method was chosen as a reference. Simultaneously, a study of the quality of liquid phase labeling by 111indium was done. The labeling process quality for each phase of the meal was assessed: a) in vitro, after incubation of the meal with human gastric juice (n = 12); b) in vivo, after meal ingestion and sequential collection of gastric contents by aspiration (n = 4). Furthermore, in 8 healthy volunteers, gastric emptying curves of the solid and liquid phases of the meal were determined scintigraphically and compared. Our results showed: a) for the solid phase: a good specificity of the marker, which was assessed in vitro and in vivo, after liver labeling with multipuncture technique (89 p. 100 and 92 p. 100 after 180 min, respectively); b) for the liquid phase: a good specificity of the marker in vitro and a poor specificity in vivo (82 p. 100 and 27 p. 100 after 180 min, respectively); c) similar half-gastric emptying times and cumulative percentages for the solid and liquid phases with both liver labeling methods. In conclusion, the multipuncture technique for chicken liver labeling may be used for gastric emptying studies in humans. SN - 0399-8320 UR - https://www.unboundmedicine.com/medline/citation/3996817/[Gastric_emptying_of_a_solid_liquid_meal_in_normal_subjects:_validity_of_the_labeling__99mTc__of_chicken_liver_by_a_multipuncture_technic]_ DB - PRIME DP - Unbound Medicine ER -