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The value of bacteriology and serology in the diagnosis of cellulitis and erysipelas.
Br J Dermatol 1985; 112(5):559-67BJ

Abstract

Patients diagnosed as suffering from erysipelas or cellulitis were subjected to bacteriological and serological investigations. The serological tests used included the anti-streptolysin O reaction (ASO), the anti-deoxyribonuclease B test (ADB) and the anti-hyaluronidase tests (AHT) that are specific both for the group A streptococcus (Streptococcus pyogenes) and for the human pyogenic streptococci of group C or group G. Antibody tests to the alpha-lysin and the nuclease of Staphylococcus aureus were also employed. Conventional bacteriological culture methods were used plus needle aspiration of injected saline in most patients with erysipelas, but recognized pathogens were isolated in only 42% of cases. Our results indicate the limitations of these tests for making initial diagnoses and deciding treatment. Serial serological testing was very successful in differentiating cellulitis due to group A, C or G haemolytic streptococci, or occasionally Staphylococcus aureus, but was positive in only 40% of cases of erysipelas.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

4005155

Citation

Leppard, B J., et al. "The Value of Bacteriology and Serology in the Diagnosis of Cellulitis and Erysipelas." The British Journal of Dermatology, vol. 112, no. 5, 1985, pp. 559-67.
Leppard BJ, Seal DV, Colman G, et al. The value of bacteriology and serology in the diagnosis of cellulitis and erysipelas. Br J Dermatol. 1985;112(5):559-67.
Leppard, B. J., Seal, D. V., Colman, G., & Hallas, G. (1985). The value of bacteriology and serology in the diagnosis of cellulitis and erysipelas. The British Journal of Dermatology, 112(5), pp. 559-67.
Leppard BJ, et al. The Value of Bacteriology and Serology in the Diagnosis of Cellulitis and Erysipelas. Br J Dermatol. 1985;112(5):559-67. PubMed PMID: 4005155.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The value of bacteriology and serology in the diagnosis of cellulitis and erysipelas. AU - Leppard,B J, AU - Seal,D V, AU - Colman,G, AU - Hallas,G, PY - 1985/5/1/pubmed PY - 1985/5/1/medline PY - 1985/5/1/entrez SP - 559 EP - 67 JF - The British journal of dermatology JO - Br. J. Dermatol. VL - 112 IS - 5 N2 - Patients diagnosed as suffering from erysipelas or cellulitis were subjected to bacteriological and serological investigations. The serological tests used included the anti-streptolysin O reaction (ASO), the anti-deoxyribonuclease B test (ADB) and the anti-hyaluronidase tests (AHT) that are specific both for the group A streptococcus (Streptococcus pyogenes) and for the human pyogenic streptococci of group C or group G. Antibody tests to the alpha-lysin and the nuclease of Staphylococcus aureus were also employed. Conventional bacteriological culture methods were used plus needle aspiration of injected saline in most patients with erysipelas, but recognized pathogens were isolated in only 42% of cases. Our results indicate the limitations of these tests for making initial diagnoses and deciding treatment. Serial serological testing was very successful in differentiating cellulitis due to group A, C or G haemolytic streptococci, or occasionally Staphylococcus aureus, but was positive in only 40% of cases of erysipelas. SN - 0007-0963 UR - https://www.unboundmedicine.com/medline/citation/4005155/The_value_of_bacteriology_and_serology_in_the_diagnosis_of_cellulitis_and_erysipelas_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0007-0963&date=1985&volume=112&issue=5&spage=559 DB - PRIME DP - Unbound Medicine ER -