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Adenomas of the breast and ectopic breast under lactational influences.
Hum Pathol. 1985 Jul; 16(7):707-12.HP

Abstract

The tubular adenomas, lactating adenomas, and ectopic lactation- or gestation-associated benign lesions of the breast diagnosed during a 22-year period are reported. Forty-two breast adenomas (in 28 patients) that demonstrated lactational changes are reviewed, with special attention to classification and clinical presentation. Five ectopic lactating adenomas--three axillary or in the chest wall and two vulvar, the latter occurring in the same patient--were identified in three patients. The lesions in the remaining cases were fibroadenomas with lactational changes (16 patients) and lactating or tubular adenomas (nine patients). Striking histologic and clinical similarities between the tubular and lactating adenomas and the lesions identified as lactational changes within a fibroadenoma were observed, with foci of tubular adenomatous change present within otherwise typical fibroadenomas. The overlapping morphologic spectrum and the strong association with pregnancy or lactational influences blur the distinction between these entities and suggest a common pathogenesis. The cytologic features of lactational lesions of the breast and ectopic breast pose special problems in diagnosis by fine needle aspiration.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

4007846

Citation

O'Hara, M F., and D L. Page. "Adenomas of the Breast and Ectopic Breast Under Lactational Influences." Human Pathology, vol. 16, no. 7, 1985, pp. 707-12.
O'Hara MF, Page DL. Adenomas of the breast and ectopic breast under lactational influences. Hum Pathol. 1985;16(7):707-12.
O'Hara, M. F., & Page, D. L. (1985). Adenomas of the breast and ectopic breast under lactational influences. Human Pathology, 16(7), 707-12.
O'Hara MF, Page DL. Adenomas of the Breast and Ectopic Breast Under Lactational Influences. Hum Pathol. 1985;16(7):707-12. PubMed PMID: 4007846.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Adenomas of the breast and ectopic breast under lactational influences. AU - O'Hara,M F, AU - Page,D L, PY - 1985/7/1/pubmed PY - 1985/7/1/medline PY - 1985/7/1/entrez SP - 707 EP - 12 JF - Human pathology JO - Hum. Pathol. VL - 16 IS - 7 N2 - The tubular adenomas, lactating adenomas, and ectopic lactation- or gestation-associated benign lesions of the breast diagnosed during a 22-year period are reported. Forty-two breast adenomas (in 28 patients) that demonstrated lactational changes are reviewed, with special attention to classification and clinical presentation. Five ectopic lactating adenomas--three axillary or in the chest wall and two vulvar, the latter occurring in the same patient--were identified in three patients. The lesions in the remaining cases were fibroadenomas with lactational changes (16 patients) and lactating or tubular adenomas (nine patients). Striking histologic and clinical similarities between the tubular and lactating adenomas and the lesions identified as lactational changes within a fibroadenoma were observed, with foci of tubular adenomatous change present within otherwise typical fibroadenomas. The overlapping morphologic spectrum and the strong association with pregnancy or lactational influences blur the distinction between these entities and suggest a common pathogenesis. The cytologic features of lactational lesions of the breast and ectopic breast pose special problems in diagnosis by fine needle aspiration. SN - 0046-8177 UR - https://www.unboundmedicine.com/medline/citation/4007846/Adenomas_of_the_breast_and_ectopic_breast_under_lactational_influences_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0046-8177(85)80156-8 DB - PRIME DP - Unbound Medicine ER -