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Irritable bowel syndrome and hypersensitivity to food.
Ann Allergy. 1985 Jun; 54(6):538-40.AA

Abstract

Food hypersensitivity as a cause of irritable bowel syndrome was investigated by means of exclusion diet and blind provocation. Twelve atopic and twelve non-atopic individuals entered into the study. Skin prick testing with 20 foods and food additives and RAST specific for food only, were done in all cases. Serum IgE level was also measured. In 14 patients one or several food or additives were shown to induce the typical symptoms of IBS. In at least nine cases of atopy, an IgE-mediated mechanism could be incriminated. Among other potential pathogenetic mechanisms, the presence in the intestinal tract of yeast (Candida albicans, Geotrichum candidum) seems to be of major importance. Yeast apparently favor the development of allergic as well as pseudo-allergic reactions, at least in some patients. Finally, at least in atopic patients complaining of IBS, it is of importance to search for a food component. Dramatic clinical improvements can result from the introduction of an adequate exclusion diet.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

4014782

Citation

Petitpierre, M, et al. "Irritable Bowel Syndrome and Hypersensitivity to Food." Annals of Allergy, vol. 54, no. 6, 1985, pp. 538-40.
Petitpierre M, Gumowski P, Girard JP. Irritable bowel syndrome and hypersensitivity to food. Ann Allergy. 1985;54(6):538-40.
Petitpierre, M., Gumowski, P., & Girard, J. P. (1985). Irritable bowel syndrome and hypersensitivity to food. Annals of Allergy, 54(6), 538-40.
Petitpierre M, Gumowski P, Girard JP. Irritable Bowel Syndrome and Hypersensitivity to Food. Ann Allergy. 1985;54(6):538-40. PubMed PMID: 4014782.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Irritable bowel syndrome and hypersensitivity to food. AU - Petitpierre,M, AU - Gumowski,P, AU - Girard,J P, PY - 1985/6/1/pubmed PY - 1985/6/1/medline PY - 1985/6/1/entrez SP - 538 EP - 40 JF - Annals of allergy JO - Ann Allergy VL - 54 IS - 6 N2 - Food hypersensitivity as a cause of irritable bowel syndrome was investigated by means of exclusion diet and blind provocation. Twelve atopic and twelve non-atopic individuals entered into the study. Skin prick testing with 20 foods and food additives and RAST specific for food only, were done in all cases. Serum IgE level was also measured. In 14 patients one or several food or additives were shown to induce the typical symptoms of IBS. In at least nine cases of atopy, an IgE-mediated mechanism could be incriminated. Among other potential pathogenetic mechanisms, the presence in the intestinal tract of yeast (Candida albicans, Geotrichum candidum) seems to be of major importance. Yeast apparently favor the development of allergic as well as pseudo-allergic reactions, at least in some patients. Finally, at least in atopic patients complaining of IBS, it is of importance to search for a food component. Dramatic clinical improvements can result from the introduction of an adequate exclusion diet. SN - 0003-4738 UR - https://www.unboundmedicine.com/medline/citation/4014782/Irritable_bowel_syndrome_and_hypersensitivity_to_food_ DB - PRIME DP - Unbound Medicine ER -