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IgD myeloma with myelofibrosis and amyloidosis.
Arch Pathol Lab Med. 1977 Jan; 101(1):10-3.AP

Abstract

Two patients with IgD myeloma protein and lambda light chains are described. They had marked Bence Jones proteinuria, were treated with melphalan, prednisone, and allopurinol and died in less than one year. At autopsy, there was extensive myelofibrosis associated with neoplastic infiltrates of plasma cells in both cases. On electrophoresis, the serum and urine Bence Jones protein of one patient migrated in the alpha2 region, and the blood vessels of the other patient contained many nodular deposits of amyloid. Because these findings are rare in multiple myeloma, they may be unique to IgD myeloma.

Authors

Udoji WC
No affiliation info available
Pemmaraju S
No affiliation info available

MeSH

AgedAmyloidosisAutopsyBone MarrowFemaleHumansImmunoglobulin DImmunoglobulin lambda-ChainsKidneyMiddle AgedMultiple MyelomaPlasma CellsPrimary MyelofibrosisSpleen

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

401635

Citation

Udoji, W C., and S Pemmaraju. "IgD Myeloma With Myelofibrosis and Amyloidosis." Archives of Pathology & Laboratory Medicine, vol. 101, no. 1, 1977, pp. 10-3.
Udoji WC, Pemmaraju S. IgD myeloma with myelofibrosis and amyloidosis. Arch Pathol Lab Med. 1977;101(1):10-3.
Udoji, W. C., & Pemmaraju, S. (1977). IgD myeloma with myelofibrosis and amyloidosis. Archives of Pathology & Laboratory Medicine, 101(1), 10-3.
Udoji WC, Pemmaraju S. IgD Myeloma With Myelofibrosis and Amyloidosis. Arch Pathol Lab Med. 1977;101(1):10-3. PubMed PMID: 401635.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - IgD myeloma with myelofibrosis and amyloidosis. AU - Udoji,W C, AU - Pemmaraju,S, PY - 1977/1/1/pubmed PY - 1977/1/1/medline PY - 1977/1/1/entrez SP - 10 EP - 3 JF - Archives of pathology & laboratory medicine JO - Arch Pathol Lab Med VL - 101 IS - 1 N2 - Two patients with IgD myeloma protein and lambda light chains are described. They had marked Bence Jones proteinuria, were treated with melphalan, prednisone, and allopurinol and died in less than one year. At autopsy, there was extensive myelofibrosis associated with neoplastic infiltrates of plasma cells in both cases. On electrophoresis, the serum and urine Bence Jones protein of one patient migrated in the alpha2 region, and the blood vessels of the other patient contained many nodular deposits of amyloid. Because these findings are rare in multiple myeloma, they may be unique to IgD myeloma. SN - 0003-9985 UR - https://www.unboundmedicine.com/medline/citation/401635/IgD_myeloma_with_myelofibrosis_and_amyloidosis_ L2 - http://www.diseaseinfosearch.org/result/380 DB - PRIME DP - Unbound Medicine ER -