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[TRH refractory TSH values, triiodothyronine levels and T3/T4 quotients in hypothyroid children treated with T3/T4 preparations (author's transl)].
Klin Wochenschr 1977; 55(3):131-5KW

Abstract

TRH-tests, triiodothyronine (T3), TBI, and thyroxine (T4) determinations were carried out in 23 children with primary hypothyroidism treated with T3/T4-preparations. T3/T4 quotients were calculated. 7 out of 10 patients with TRH refractory TSH values and normal T4 levels had T3 values above normal range. In 6 of them pathologically elevated T3/T4 quotients could be observed. A TSH refractory TSH suppression was only found in patients with superior normal T4 values. After a reduction of the replacement doses the T3 values were normal. The findings show--that not only the T4 values should be controlled under treatment with thyroid preparations but also the T3 and TSH serum levels. The replacement therapy of hypothyroidism with T3/T4 preparations in proportion 1:4 should be revised.

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

401919

Citation

Hesse, V, et al. "[TRH Refractory TSH Values, Triiodothyronine Levels and T3/T4 Quotients in Hypothyroid Children Treated With T3/T4 Preparations (author's Transl)]." Klinische Wochenschrift, vol. 55, no. 3, 1977, pp. 131-5.
Hesse V, Lauterbach H, Stoll W. [TRH refractory TSH values, triiodothyronine levels and T3/T4 quotients in hypothyroid children treated with T3/T4 preparations (author's transl)]. Klin Wochenschr. 1977;55(3):131-5.
Hesse, V., Lauterbach, H., & Stoll, W. (1977). [TRH refractory TSH values, triiodothyronine levels and T3/T4 quotients in hypothyroid children treated with T3/T4 preparations (author's transl)]. Klinische Wochenschrift, 55(3), pp. 131-5.
Hesse V, Lauterbach H, Stoll W. [TRH Refractory TSH Values, Triiodothyronine Levels and T3/T4 Quotients in Hypothyroid Children Treated With T3/T4 Preparations (author's Transl)]. Klin Wochenschr. 1977 Feb 1;55(3):131-5. PubMed PMID: 401919.
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TY - JOUR T1 - [TRH refractory TSH values, triiodothyronine levels and T3/T4 quotients in hypothyroid children treated with T3/T4 preparations (author's transl)]. AU - Hesse,V, AU - Lauterbach,H, AU - Stoll,W, PY - 1977/2/1/pubmed PY - 1977/2/1/medline PY - 1977/2/1/entrez SP - 131 EP - 5 JF - Klinische Wochenschrift JO - Klin. Wochenschr. VL - 55 IS - 3 N2 - TRH-tests, triiodothyronine (T3), TBI, and thyroxine (T4) determinations were carried out in 23 children with primary hypothyroidism treated with T3/T4-preparations. T3/T4 quotients were calculated. 7 out of 10 patients with TRH refractory TSH values and normal T4 levels had T3 values above normal range. In 6 of them pathologically elevated T3/T4 quotients could be observed. A TSH refractory TSH suppression was only found in patients with superior normal T4 values. After a reduction of the replacement doses the T3 values were normal. The findings show--that not only the T4 values should be controlled under treatment with thyroid preparations but also the T3 and TSH serum levels. The replacement therapy of hypothyroidism with T3/T4 preparations in proportion 1:4 should be revised. SN - 0023-2173 UR - https://www.unboundmedicine.com/medline/citation/401919/[TRH_refractory_TSH_values_triiodothyronine_levels_and_T3/T4_quotients_in_hypothyroid_children_treated_with_T3/T4_preparations__author's_transl_]_ L2 - https://medlineplus.gov/hypothyroidism.html DB - PRIME DP - Unbound Medicine ER -