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Effects of two antihistaminic compounds (mequitazine, dexchlorpheniramine) on sleep. Sleep distorsion by antihistaminics.
Waking Sleeping. 1979 Jan; 3(1):57-61.WS

Abstract

Twelve healthy subjects have been given mequitazine (two 10-milligramme doses a day), dexchlorpheniramine (two 12-milligramme doses a day) and a placebo for seven days, within a cross-over balanced design. If dexchlorpheniramine induces a significant sleep distortion (slowed REM sleep cycle and decreased amount of REM sleep), no similar trend occured with mequitazine, a result that could be dose or time related.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

40345

Citation

Bassano, J L., and E J. Caille. "Effects of Two Antihistaminic Compounds (mequitazine, Dexchlorpheniramine) On Sleep. Sleep Distorsion By Antihistaminics." Waking and Sleeping, vol. 3, no. 1, 1979, pp. 57-61.
Bassano JL, Caille EJ. Effects of two antihistaminic compounds (mequitazine, dexchlorpheniramine) on sleep. Sleep distorsion by antihistaminics. Waking Sleeping. 1979;3(1):57-61.
Bassano, J. L., & Caille, E. J. (1979). Effects of two antihistaminic compounds (mequitazine, dexchlorpheniramine) on sleep. Sleep distorsion by antihistaminics. Waking and Sleeping, 3(1), 57-61.
Bassano JL, Caille EJ. Effects of Two Antihistaminic Compounds (mequitazine, Dexchlorpheniramine) On Sleep. Sleep Distorsion By Antihistaminics. Waking Sleeping. 1979;3(1):57-61. PubMed PMID: 40345.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of two antihistaminic compounds (mequitazine, dexchlorpheniramine) on sleep. Sleep distorsion by antihistaminics. AU - Bassano,J L, AU - Caille,E J, PY - 1979/1/1/pubmed PY - 1979/1/1/medline PY - 1979/1/1/entrez SP - 57 EP - 61 JF - Waking and sleeping JO - Waking Sleeping VL - 3 IS - 1 N2 - Twelve healthy subjects have been given mequitazine (two 10-milligramme doses a day), dexchlorpheniramine (two 12-milligramme doses a day) and a placebo for seven days, within a cross-over balanced design. If dexchlorpheniramine induces a significant sleep distortion (slowed REM sleep cycle and decreased amount of REM sleep), no similar trend occured with mequitazine, a result that could be dose or time related. SN - 0340-0905 UR - https://www.unboundmedicine.com/medline/citation/40345/Effects_of_two_antihistaminic_compounds__mequitazine_dexchlorpheniramine__on_sleep__Sleep_distorsion_by_antihistaminics_ DB - PRIME DP - Unbound Medicine ER -