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Antileukemia activity in the Osillatoriaceae: isolation of Debromoaplysiatoxin from Lyngbya.
Science. 1977 Apr 29; 196(4289):538-40.Sci

Abstract

Chloroform extracts of several seaweeds, of the family Oscillatoriaceae, from Enewetak Atoll, Marshall Islands, display activity against P-388 lymphocytic mouse leukemia. A P-388 active compound, debromoaplysiatoxin, has been isolated from Lyngbya gracilis and characterized. This compound also has dermonecrotic activity and may be the dermatitis-producing substance in L. majuscula, the causative agent of "swimmers' itch" outbreaks in Hawaiian waters.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

403608

Citation

Mynderse, J S., et al. "Antileukemia Activity in the Osillatoriaceae: Isolation of Debromoaplysiatoxin From Lyngbya." Science (New York, N.Y.), vol. 196, no. 4289, 1977, pp. 538-40.
Mynderse JS, Moore RE, Kashiwagi M, et al. Antileukemia activity in the Osillatoriaceae: isolation of Debromoaplysiatoxin from Lyngbya. Science. 1977;196(4289):538-40.
Mynderse, J. S., Moore, R. E., Kashiwagi, M., & Norton, T. R. (1977). Antileukemia activity in the Osillatoriaceae: isolation of Debromoaplysiatoxin from Lyngbya. Science (New York, N.Y.), 196(4289), 538-40.
Mynderse JS, et al. Antileukemia Activity in the Osillatoriaceae: Isolation of Debromoaplysiatoxin From Lyngbya. Science. 1977 Apr 29;196(4289):538-40. PubMed PMID: 403608.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antileukemia activity in the Osillatoriaceae: isolation of Debromoaplysiatoxin from Lyngbya. AU - Mynderse,J S, AU - Moore,R E, AU - Kashiwagi,M, AU - Norton,T R, PY - 1977/4/29/pubmed PY - 1977/4/29/medline PY - 1977/4/29/entrez SP - 538 EP - 40 JF - Science (New York, N.Y.) JO - Science VL - 196 IS - 4289 N2 - Chloroform extracts of several seaweeds, of the family Oscillatoriaceae, from Enewetak Atoll, Marshall Islands, display activity against P-388 lymphocytic mouse leukemia. A P-388 active compound, debromoaplysiatoxin, has been isolated from Lyngbya gracilis and characterized. This compound also has dermonecrotic activity and may be the dermatitis-producing substance in L. majuscula, the causative agent of "swimmers' itch" outbreaks in Hawaiian waters. SN - 0036-8075 UR - https://www.unboundmedicine.com/medline/citation/403608/Antileukemia_activity_in_the_Osillatoriaceae:_isolation_of_Debromoaplysiatoxin_from_Lyngbya_ L2 - https://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=403608 DB - PRIME DP - Unbound Medicine ER -