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Intra-abdominal complications of cystic fibrosis.
J Pediatr Surg. 1985 Aug; 20(4):431-5.JP

Abstract

In recent years patients with cystic fibrosis (CF) have experienced longterm survival and have demonstrated a number of intra-abdominal complications. This report evaluates the intra-abdominal complications seen in 69 of 189 children with cystic fibrosis from 1972 to 1983. Forty-one patients were boys and twenty-eight girls. Complications occurred in 36 neonates, with meconium ileus (MI) noted in 33 and giant cystic meconium peritonitis (GCMP) in 3. Meconium ileus equivalent occurred in seven older children presenting with bowel obstruction. In addition, rectal prolapse occurred in 12, inguinal hernia in 10, intussusception in 3, cholelithiasis in 3, GE reflux in 4, stress ulcer in 1 and appendicitis in 1. Three infants with GCMP survived resection and enterostomy. Infants with MI were divided into simple (15) or complicated (18) cases. Nonoperative therapy using gastrografin enema was successful in three of eight with simple MI. Operative enterotomy and irrigation was successful in three cases while resection and enterostomy was done in nine. MI was complicated by atresia, volvulus and/or perforation in 18 cases requiring resection and anastomosis or enterostomy. Survival for MI was 86% compared to 36% in 25 MI patients treated in the previous two decades. Meconium ileus equivalent was successfully managed using gastrografin enema in five of seven children. Only 3 of 12 children with rectal prolapse required repair. Two cases of intussusception were reduced while one required resection. Three of 10 children had hernia recurrence due to chronic pulmonary problems.(

ABSTRACT

TRUNCATED AT 250 WORDS)

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

4045671

Citation

Gross, K, et al. "Intra-abdominal Complications of Cystic Fibrosis." Journal of Pediatric Surgery, vol. 20, no. 4, 1985, pp. 431-5.
Gross K, Desanto A, Grosfeld JL, et al. Intra-abdominal complications of cystic fibrosis. J Pediatr Surg. 1985;20(4):431-5.
Gross, K., Desanto, A., Grosfeld, J. L., West, K. W., & Eigen, H. (1985). Intra-abdominal complications of cystic fibrosis. Journal of Pediatric Surgery, 20(4), 431-5.
Gross K, et al. Intra-abdominal Complications of Cystic Fibrosis. J Pediatr Surg. 1985;20(4):431-5. PubMed PMID: 4045671.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intra-abdominal complications of cystic fibrosis. AU - Gross,K, AU - Desanto,A, AU - Grosfeld,J L, AU - West,K W, AU - Eigen,H, PY - 1985/8/1/pubmed PY - 1985/8/1/medline PY - 1985/8/1/entrez SP - 431 EP - 5 JF - Journal of pediatric surgery JO - J. Pediatr. Surg. VL - 20 IS - 4 N2 - In recent years patients with cystic fibrosis (CF) have experienced longterm survival and have demonstrated a number of intra-abdominal complications. This report evaluates the intra-abdominal complications seen in 69 of 189 children with cystic fibrosis from 1972 to 1983. Forty-one patients were boys and twenty-eight girls. Complications occurred in 36 neonates, with meconium ileus (MI) noted in 33 and giant cystic meconium peritonitis (GCMP) in 3. Meconium ileus equivalent occurred in seven older children presenting with bowel obstruction. In addition, rectal prolapse occurred in 12, inguinal hernia in 10, intussusception in 3, cholelithiasis in 3, GE reflux in 4, stress ulcer in 1 and appendicitis in 1. Three infants with GCMP survived resection and enterostomy. Infants with MI were divided into simple (15) or complicated (18) cases. Nonoperative therapy using gastrografin enema was successful in three of eight with simple MI. Operative enterotomy and irrigation was successful in three cases while resection and enterostomy was done in nine. MI was complicated by atresia, volvulus and/or perforation in 18 cases requiring resection and anastomosis or enterostomy. Survival for MI was 86% compared to 36% in 25 MI patients treated in the previous two decades. Meconium ileus equivalent was successfully managed using gastrografin enema in five of seven children. Only 3 of 12 children with rectal prolapse required repair. Two cases of intussusception were reduced while one required resection. Three of 10 children had hernia recurrence due to chronic pulmonary problems.(ABSTRACT TRUNCATED AT 250 WORDS) SN - 0022-3468 UR - https://www.unboundmedicine.com/medline/citation/4045671/Intra_abdominal_complications_of_cystic_fibrosis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S002234688500094X DB - PRIME DP - Unbound Medicine ER -