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Adverse reactions to sulfites.
CMAJ 1985; 133(9):865-7, 880CMAJ

Abstract

Sulfites are widely used as preservatives in the food and pharmaceutical industries. In the United States more than 250 cases of sulfite-related adverse reactions, including anaphylactic shock, asthmatic attacks, urticaria and angioedema, nausea, abdominal pain and diarrhea, seizures and death, have been reported, including 6 deaths allegedly associated with restaurant food containing sulfites. In Canada 10 sulfite-related adverse reactions have been documented, and 1 death suspected to be sulfite-related has occurred. The exact mechanism of sulfite-induced reactions is unknown. Practising physicians should be aware of the clinical manifestations of sulfite-related adverse reactions as well as which foods and pharmaceuticals contain sulfites. Cases should be reported to health officials and proper advice given to the victims to prevent further exposure to sulfites. The food industry, including beer and wine manufacturers, and the pharmaceutical industry should consider using alternative preservatives. In the interim, they should list any sulfites in their products.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

4052897

Citation

Yang, W H., and E C. Purchase. "Adverse Reactions to Sulfites." CMAJ : Canadian Medical Association Journal = Journal De l'Association Medicale Canadienne, vol. 133, no. 9, 1985, pp. 865-7, 880.
Yang WH, Purchase EC. Adverse reactions to sulfites. CMAJ. 1985;133(9):865-7, 880.
Yang, W. H., & Purchase, E. C. (1985). Adverse reactions to sulfites. CMAJ : Canadian Medical Association Journal = Journal De l'Association Medicale Canadienne, 133(9), pp. 865-7, 880.
Yang WH, Purchase EC. Adverse Reactions to Sulfites. CMAJ. 1985 Nov 1;133(9):865-7, 880. PubMed PMID: 4052897.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Adverse reactions to sulfites. AU - Yang,W H, AU - Purchase,E C, PY - 1985/11/1/pubmed PY - 1985/11/1/medline PY - 1985/11/1/entrez SP - 865-7, 880 JF - CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne JO - CMAJ VL - 133 IS - 9 N2 - Sulfites are widely used as preservatives in the food and pharmaceutical industries. In the United States more than 250 cases of sulfite-related adverse reactions, including anaphylactic shock, asthmatic attacks, urticaria and angioedema, nausea, abdominal pain and diarrhea, seizures and death, have been reported, including 6 deaths allegedly associated with restaurant food containing sulfites. In Canada 10 sulfite-related adverse reactions have been documented, and 1 death suspected to be sulfite-related has occurred. The exact mechanism of sulfite-induced reactions is unknown. Practising physicians should be aware of the clinical manifestations of sulfite-related adverse reactions as well as which foods and pharmaceuticals contain sulfites. Cases should be reported to health officials and proper advice given to the victims to prevent further exposure to sulfites. The food industry, including beer and wine manufacturers, and the pharmaceutical industry should consider using alternative preservatives. In the interim, they should list any sulfites in their products. SN - 0820-3946 UR - https://www.unboundmedicine.com/medline/citation/4052897/Adverse_reactions_to_sulfites_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/4052897/ DB - PRIME DP - Unbound Medicine ER -