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Parietal cell vagotomy in the surgical treatment of chronic duodenal, pyloric and prepyloric ulcer disease.
Int Surg. 1985 Apr-Jun; 70(2):139-44.IS

Abstract

During the 1970s, parietal cell vagotomy (PCV) gradually became accepted as a suitable method in the surgical treatment of prepyloric, pyloric and duodenal ulcer disease. This study reports the data from a study of 405 consecutive patients with chronic ulcer disease treated with PCV. Mortality was low (0.5%) and there were few postoperative sequelae (periodic loose stools in 2% and mild dumping in 2%). Reduction in basal acid output was 75% and in pentagastrin stimulated acid secretion 50%. The ulcer recurrence rate was initially higher in pyloric-prepyloric (PU/PPU) than in duodenal ulcer disease but after the seventh postoperative year this difference was no longer statistically significant. The accumulated recurrence rate was 17.5%. Few side effects and a comparatively low recurrence rate makes PCV the method of choice in the surgical treatment of peptic ulcer disease.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

4055278

Citation

Graffner, H O., et al. "Parietal Cell Vagotomy in the Surgical Treatment of Chronic Duodenal, Pyloric and Prepyloric Ulcer Disease." International Surgery, vol. 70, no. 2, 1985, pp. 139-44.
Graffner HO, Liedberg GF, Oscarson JE. Parietal cell vagotomy in the surgical treatment of chronic duodenal, pyloric and prepyloric ulcer disease. Int Surg. 1985;70(2):139-44.
Graffner, H. O., Liedberg, G. F., & Oscarson, J. E. (1985). Parietal cell vagotomy in the surgical treatment of chronic duodenal, pyloric and prepyloric ulcer disease. International Surgery, 70(2), 139-44.
Graffner HO, Liedberg GF, Oscarson JE. Parietal Cell Vagotomy in the Surgical Treatment of Chronic Duodenal, Pyloric and Prepyloric Ulcer Disease. Int Surg. 1985 Apr-Jun;70(2):139-44. PubMed PMID: 4055278.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Parietal cell vagotomy in the surgical treatment of chronic duodenal, pyloric and prepyloric ulcer disease. AU - Graffner,H O, AU - Liedberg,G F, AU - Oscarson,J E, PY - 1985/4/1/pubmed PY - 1985/4/1/medline PY - 1985/4/1/entrez SP - 139 EP - 44 JF - International surgery JO - Int Surg VL - 70 IS - 2 N2 - During the 1970s, parietal cell vagotomy (PCV) gradually became accepted as a suitable method in the surgical treatment of prepyloric, pyloric and duodenal ulcer disease. This study reports the data from a study of 405 consecutive patients with chronic ulcer disease treated with PCV. Mortality was low (0.5%) and there were few postoperative sequelae (periodic loose stools in 2% and mild dumping in 2%). Reduction in basal acid output was 75% and in pentagastrin stimulated acid secretion 50%. The ulcer recurrence rate was initially higher in pyloric-prepyloric (PU/PPU) than in duodenal ulcer disease but after the seventh postoperative year this difference was no longer statistically significant. The accumulated recurrence rate was 17.5%. Few side effects and a comparatively low recurrence rate makes PCV the method of choice in the surgical treatment of peptic ulcer disease. SN - 0020-8868 UR - https://www.unboundmedicine.com/medline/citation/4055278/Parietal_cell_vagotomy_in_the_surgical_treatment_of_chronic_duodenal_pyloric_and_prepyloric_ulcer_disease_ DB - PRIME DP - Unbound Medicine ER -