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Antigens in pigeon breeder's disease: the use of pigeon dropping antigens in detecting antibody activity.
Clin Allergy. 1977 Mar; 7(2):103-8.CA

Abstract

Sera from patients with pigeon breeder's disease were analysed for precipitating antibodies by immunodiffusion and immunoelectrophoresis using whole pigeon dropping extract (PDE) and a purified fraction of PDE (PDE1) as antigens. For comparison, sera from asymptomatic pigeon breeders and normal individuals were also tested for precipitating antibodies. Whereas whole PDE formed precipitin lines with normal serum as well as with serum from symptomatic and asymptomatic pigeon breeders, PDE1 formed precipitin lines only with serum from individuals exposed to pigeons, This suggests that whole PDE forms non-specific (non-antigen-antibody reactions) as well as specific precipitin lines, while PDE1 appears to form only specific lines. These data indicate that whole PDE has limited usefulness in studies of pigeon breeder's disease. It is also possible that PDE1 will be useful in studies of this disease.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

406101

Citation

Tebo, T H., et al. "Antigens in Pigeon Breeder's Disease: the Use of Pigeon Dropping Antigens in Detecting Antibody Activity." Clinical Allergy, vol. 7, no. 2, 1977, pp. 103-8.
Tebo TH, Moore VL, Fink JN. Antigens in pigeon breeder's disease: the use of pigeon dropping antigens in detecting antibody activity. Clin Allergy. 1977;7(2):103-8.
Tebo, T. H., Moore, V. L., & Fink, J. N. (1977). Antigens in pigeon breeder's disease: the use of pigeon dropping antigens in detecting antibody activity. Clinical Allergy, 7(2), 103-8.
Tebo TH, Moore VL, Fink JN. Antigens in Pigeon Breeder's Disease: the Use of Pigeon Dropping Antigens in Detecting Antibody Activity. Clin Allergy. 1977;7(2):103-8. PubMed PMID: 406101.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antigens in pigeon breeder's disease: the use of pigeon dropping antigens in detecting antibody activity. AU - Tebo,T H, AU - Moore,V L, AU - Fink,J N, PY - 1977/3/1/pubmed PY - 1977/3/1/medline PY - 1977/3/1/entrez SP - 103 EP - 8 JF - Clinical allergy JO - Clin Allergy VL - 7 IS - 2 N2 - Sera from patients with pigeon breeder's disease were analysed for precipitating antibodies by immunodiffusion and immunoelectrophoresis using whole pigeon dropping extract (PDE) and a purified fraction of PDE (PDE1) as antigens. For comparison, sera from asymptomatic pigeon breeders and normal individuals were also tested for precipitating antibodies. Whereas whole PDE formed precipitin lines with normal serum as well as with serum from symptomatic and asymptomatic pigeon breeders, PDE1 formed precipitin lines only with serum from individuals exposed to pigeons, This suggests that whole PDE forms non-specific (non-antigen-antibody reactions) as well as specific precipitin lines, while PDE1 appears to form only specific lines. These data indicate that whole PDE has limited usefulness in studies of pigeon breeder's disease. It is also possible that PDE1 will be useful in studies of this disease. SN - 0009-9090 UR - https://www.unboundmedicine.com/medline/citation/406101/Antigens_in_pigeon_breeder's_disease:_the_use_of_pigeon_dropping_antigens_in_detecting_antibody_activity_ DB - PRIME DP - Unbound Medicine ER -