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Evaluation of the body iron status of native Canadians.
Can Med Assoc J. 1979 Feb 03; 120(3):285-9.CM

Abstract

The serum ferritin concentration was measured in 1417 Indians and 310 Inuit aged 1 to 89 years. The subjects were initially selected to produce a representative sample of the entire native population, but the rate of nonresponse was high, and the results reported in this paper are representative only of the people studied.In males the median serum ferritin values increased during early life and tended to plateau after the age of 30 years. In females the median values rose during childhood, tended to plateau during adolescence, increased slightly during the reproductive period, then gradually rose thereafter. Ranges of values were wide in all age groups, reflecting the variations in body iron stores. When compared with the Inuit, the Indians had a significantly higher prevalence of abnormal serum ferritin values.From an analysis of the serum ferritin values in Indians it is probable that iron stores were reduced in approximately 30% of children, 40% of adolescents, 34% of nonpregnant women of reproductive age, 11% of older women and 5% of adult males. The corresponding figures for the Inuit were 15%, 23%, 22%, 6% and 1%. In contrast, iron deficiency anemia was found in only 3% to 4% of native peoples. If "normality" requires more than small amounts of iron stores to meet physiologic needs, the results suggest a high probability of iron deficiency in 20% to 40% of native children, adolescents and nonpregnant women of reproductive age, and in 0% to 10% of other subjects; but if "normality" is defined as adequate iron stores for erythropoiesis the prevalence of iron deficiency was approximately 1% to 2% in children and adolescents, 3% to 5% in women and less than 1% in adult males.

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Authors

Valberg LS
No affiliation info available
Birkett N
No affiliation info available
Haist J
No affiliation info available
Zamecnik J
No affiliation info available
Pelletier O
No affiliation info available

MeSH

AdolescentAdultAge FactorsAnemia, HypochromicCanadaChildChild, PreschoolDietFemaleFerritinsHemoglobinsHumansIndians, North AmericanInfantInuitsIronIron DeficienciesMaleMiddle AgedNutrition SurveysNutritional RequirementsPregnancy

Pub Type(s)

Journal Article

Language

eng

PubMed ID

427665

Citation

Valberg, L S., et al. "Evaluation of the Body Iron Status of Native Canadians." Canadian Medical Association Journal, vol. 120, no. 3, 1979, pp. 285-9.
Valberg LS, Birkett N, Haist J, et al. Evaluation of the body iron status of native Canadians. Can Med Assoc J. 1979;120(3):285-9.
Valberg, L. S., Birkett, N., Haist, J., Zamecnik, J., & Pelletier, O. (1979). Evaluation of the body iron status of native Canadians. Canadian Medical Association Journal, 120(3), 285-9.
Valberg LS, et al. Evaluation of the Body Iron Status of Native Canadians. Can Med Assoc J. 1979 Feb 3;120(3):285-9. PubMed PMID: 427665.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of the body iron status of native Canadians. AU - Valberg,L S, AU - Birkett,N, AU - Haist,J, AU - Zamecnik,J, AU - Pelletier,O, PY - 1979/2/3/pubmed PY - 1979/2/3/medline PY - 1979/2/3/entrez SP - 285 EP - 9 JF - Canadian Medical Association journal JO - Can Med Assoc J VL - 120 IS - 3 N2 - The serum ferritin concentration was measured in 1417 Indians and 310 Inuit aged 1 to 89 years. The subjects were initially selected to produce a representative sample of the entire native population, but the rate of nonresponse was high, and the results reported in this paper are representative only of the people studied.In males the median serum ferritin values increased during early life and tended to plateau after the age of 30 years. In females the median values rose during childhood, tended to plateau during adolescence, increased slightly during the reproductive period, then gradually rose thereafter. Ranges of values were wide in all age groups, reflecting the variations in body iron stores. When compared with the Inuit, the Indians had a significantly higher prevalence of abnormal serum ferritin values.From an analysis of the serum ferritin values in Indians it is probable that iron stores were reduced in approximately 30% of children, 40% of adolescents, 34% of nonpregnant women of reproductive age, 11% of older women and 5% of adult males. The corresponding figures for the Inuit were 15%, 23%, 22%, 6% and 1%. In contrast, iron deficiency anemia was found in only 3% to 4% of native peoples. If "normality" requires more than small amounts of iron stores to meet physiologic needs, the results suggest a high probability of iron deficiency in 20% to 40% of native children, adolescents and nonpregnant women of reproductive age, and in 0% to 10% of other subjects; but if "normality" is defined as adequate iron stores for erythropoiesis the prevalence of iron deficiency was approximately 1% to 2% in children and adolescents, 3% to 5% in women and less than 1% in adult males. SN - 0008-4409 UR - https://www.unboundmedicine.com/medline/citation/427665/Evaluation_of_the_body_iron_status_of_native_Canadians_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/427665/ DB - PRIME DP - Unbound Medicine ER -