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Zollinger-Ellison syndrome associated with parathyroid adenomas and ectopic gastric tissue in the lower esophageal mucosa.
Can J Surg. 1979 Jan; 22(1):71-8.CJ

Abstract

A rare case of the Zollinger-Ellison syndrome associated with hyperparathyroidism and ectopic gastric tissue in the lower esophageal mucosa is reported. Preoperatively the patient, a 53-year-old woman, had hyperchlorhydria and her fasting serum gastrin concentration was mildly elevated. There was a considerable increase in the gastric acid output and concentration of serum calcium after secretin infusion. At operation the patient had a gastric ulcer 10 cm in diameter, an islet cell tumour of the pancreas 14 cm in diameter, and ectopic gastric mucosa in the distal third of the esophagus. A gastrectomy was perfomed, the pancreatic tumour excised and part of the distal esophagus removed through a left thoracotomy. Four months after the operation the gastrin concentration had returned to low normal, but the serum calcium values remained high. One month later two parathyroid adenomas were removed which effectively cured the hypercalcemia.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

445242

Citation

Nakayasu, A, et al. "Zollinger-Ellison Syndrome Associated With Parathyroid Adenomas and Ectopic Gastric Tissue in the Lower Esophageal Mucosa." Canadian Journal of Surgery. Journal Canadien De Chirurgie, vol. 22, no. 1, 1979, pp. 71-8.
Nakayasu A, Dowell AJ, Reynolds C, et al. Zollinger-Ellison syndrome associated with parathyroid adenomas and ectopic gastric tissue in the lower esophageal mucosa. Can J Surg. 1979;22(1):71-8.
Nakayasu, A., Dowell, A. J., Reynolds, C., Stordy, S. N., & Cleator, I. G. (1979). Zollinger-Ellison syndrome associated with parathyroid adenomas and ectopic gastric tissue in the lower esophageal mucosa. Canadian Journal of Surgery. Journal Canadien De Chirurgie, 22(1), 71-8.
Nakayasu A, et al. Zollinger-Ellison Syndrome Associated With Parathyroid Adenomas and Ectopic Gastric Tissue in the Lower Esophageal Mucosa. Can J Surg. 1979;22(1):71-8. PubMed PMID: 445242.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Zollinger-Ellison syndrome associated with parathyroid adenomas and ectopic gastric tissue in the lower esophageal mucosa. AU - Nakayasu,A, AU - Dowell,A J, AU - Reynolds,C, AU - Stordy,S N, AU - Cleator,I G, PY - 1979/1/1/pubmed PY - 1979/1/1/medline PY - 1979/1/1/entrez SP - 71 EP - 8 JF - Canadian journal of surgery. Journal canadien de chirurgie JO - Can J Surg VL - 22 IS - 1 N2 - A rare case of the Zollinger-Ellison syndrome associated with hyperparathyroidism and ectopic gastric tissue in the lower esophageal mucosa is reported. Preoperatively the patient, a 53-year-old woman, had hyperchlorhydria and her fasting serum gastrin concentration was mildly elevated. There was a considerable increase in the gastric acid output and concentration of serum calcium after secretin infusion. At operation the patient had a gastric ulcer 10 cm in diameter, an islet cell tumour of the pancreas 14 cm in diameter, and ectopic gastric mucosa in the distal third of the esophagus. A gastrectomy was perfomed, the pancreatic tumour excised and part of the distal esophagus removed through a left thoracotomy. Four months after the operation the gastrin concentration had returned to low normal, but the serum calcium values remained high. One month later two parathyroid adenomas were removed which effectively cured the hypercalcemia. SN - 0008-428X UR - https://www.unboundmedicine.com/medline/citation/445242/Zollinger_Ellison_syndrome_associated_with_parathyroid_adenomas_and_ectopic_gastric_tissue_in_the_lower_esophageal_mucosa_ L2 - http://www.diseaseinfosearch.org/result/7600 DB - PRIME DP - Unbound Medicine ER -