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The small-intestinal mucosa in cow's milk allergy.
Lancet 1975; 1(7899):136-4Lct

Abstract

Two infants investigated for allergy to cow's milk proteins exhibited a local reaginic reaction in the small intestine after ingesting cow's milk, as shown by increased mucosal IgE plasma-cells and degranulation of mast cells. IgM plasma-cells and the staining of connective tissue and basement membranes with antisera to IgG and C3 complement were also increased, indicating several simultaneous immune reactions in the intestinal mucosa. These findings may provide a sound basis for diagnosis of such an allergy and for the treatment of similar patients with disodium cromoglycate.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

46052

Citation

Shiner, M, et al. "The Small-intestinal Mucosa in Cow's Milk Allergy." Lancet (London, England), vol. 1, no. 7899, 1975, pp. 136-4.
Shiner M, Ballard J, Smith ME. The small-intestinal mucosa in cow's milk allergy. Lancet. 1975;1(7899):136-4.
Shiner, M., Ballard, J., & Smith, M. E. (1975). The small-intestinal mucosa in cow's milk allergy. Lancet (London, England), 1(7899), pp. 136-4.
Shiner M, Ballard J, Smith ME. The Small-intestinal Mucosa in Cow's Milk Allergy. Lancet. 1975 Jan 18;1(7899):136-4. PubMed PMID: 46052.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The small-intestinal mucosa in cow's milk allergy. AU - Shiner,M, AU - Ballard,J, AU - Smith,M E, PY - 1975/1/18/pubmed PY - 1975/1/18/medline PY - 1975/1/18/entrez SP - 136 EP - 4 JF - Lancet (London, England) JO - Lancet VL - 1 IS - 7899 N2 - Two infants investigated for allergy to cow's milk proteins exhibited a local reaginic reaction in the small intestine after ingesting cow's milk, as shown by increased mucosal IgE plasma-cells and degranulation of mast cells. IgM plasma-cells and the staining of connective tissue and basement membranes with antisera to IgG and C3 complement were also increased, indicating several simultaneous immune reactions in the intestinal mucosa. These findings may provide a sound basis for diagnosis of such an allergy and for the treatment of similar patients with disodium cromoglycate. SN - 0140-6736 UR - https://www.unboundmedicine.com/medline/citation/46052/The_small_intestinal_mucosa_in_cow's_milk_allergy_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0140-6736(75)90051-3 DB - PRIME DP - Unbound Medicine ER -