Tags

Type your tag names separated by a space and hit enter

Experimental allergic encephalomyelitis in resistant and susceptible guinea pigs: in vivo and in vitro correlates.
J Immunol. 1975 Feb; 114(2 Pt 1):546-9.JI

Abstract

Strain 2 guinea pigs develop less severe experimental allergic encephalomyelitis than do strain 13 and Hartley guinea pigs when sensitized with equivalent amounts of homologous myelin basic protein (BP) in complete Freund's adjuvant. In vivo and in vitro correlates of delayed hypersensitivity to myelin basic protein are depressed in the strain 2 guinea pigs relative to the two susceptible strains. The incidence of circulating anti-BP antibodies is also lower in sera from strain 2 guinea pigs than in sera from strain 13 or Hartley guinea pigs. There was no difference among the three strains in their ability to mount delayed hypersensitivity to tuberculin, nor in the response of their cells to PHA in vitro.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

47353

Citation

Lisak, R P., et al. "Experimental Allergic Encephalomyelitis in Resistant and Susceptible Guinea Pigs: in Vivo and in Vitro Correlates." Journal of Immunology (Baltimore, Md. : 1950), vol. 114, no. 2 Pt 1, 1975, pp. 546-9.
Lisak RP, Zweiman B, Kies MW, et al. Experimental allergic encephalomyelitis in resistant and susceptible guinea pigs: in vivo and in vitro correlates. J Immunol. 1975;114(2 Pt 1):546-9.
Lisak, R. P., Zweiman, B., Kies, M. W., & Driscoll, B. (1975). Experimental allergic encephalomyelitis in resistant and susceptible guinea pigs: in vivo and in vitro correlates. Journal of Immunology (Baltimore, Md. : 1950), 114(2 Pt 1), 546-9.
Lisak RP, et al. Experimental Allergic Encephalomyelitis in Resistant and Susceptible Guinea Pigs: in Vivo and in Vitro Correlates. J Immunol. 1975;114(2 Pt 1):546-9. PubMed PMID: 47353.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Experimental allergic encephalomyelitis in resistant and susceptible guinea pigs: in vivo and in vitro correlates. AU - Lisak,R P, AU - Zweiman,B, AU - Kies,M W, AU - Driscoll,B, PY - 1975/2/1/pubmed PY - 1975/2/1/medline PY - 1975/2/1/entrez SP - 546 EP - 9 JF - Journal of immunology (Baltimore, Md. : 1950) JO - J Immunol VL - 114 IS - 2 Pt 1 N2 - Strain 2 guinea pigs develop less severe experimental allergic encephalomyelitis than do strain 13 and Hartley guinea pigs when sensitized with equivalent amounts of homologous myelin basic protein (BP) in complete Freund's adjuvant. In vivo and in vitro correlates of delayed hypersensitivity to myelin basic protein are depressed in the strain 2 guinea pigs relative to the two susceptible strains. The incidence of circulating anti-BP antibodies is also lower in sera from strain 2 guinea pigs than in sera from strain 13 or Hartley guinea pigs. There was no difference among the three strains in their ability to mount delayed hypersensitivity to tuberculin, nor in the response of their cells to PHA in vitro. SN - 0022-1767 UR - https://www.unboundmedicine.com/medline/citation/47353/Experimental_allergic_encephalomyelitis_in_resistant_and_susceptible_guinea_pigs:_in_vivo_and_in_vitro_correlates_ L2 - https://www.jimmunol.org/lookup/pmidlookup?view=long&pmid=47353 DB - PRIME DP - Unbound Medicine ER -