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Cardiac findings in Charcot-Marie-Tooth disease. A prospective study of 68 patients.
Arch Intern Med. 1979 Oct; 139(10):1161-5.AI

Abstract

Charcot-Marie-Tooth disease (peroneal muscular atrophy) has been reported to cause cardiac arrthymias and conduction disturbances in association with peripheral muscle atrophy. To establish more accurately the frequency of such cardiac disorders in this disease, 68 patients with Charcot-Marie-Tooth disease were evaluated prospectively for evidence of cardiac involvement. Cardiac findings were limited to five patients with conduction defects, two patients with supraventricular tachycardia, two patients with ischemic heart disease, and 20 with mitral valve prolapse. The frequency of each of the abnormal cardiac findings, with the possibly emalities in the population at large. The low incidence of cardiac involvement in patients with Charcot-Marie-Tooth disease may be helpful in distinguishing this disorder from Friedreich's ataxia, an entity that may mimic Charcot-Marie-Tooth disease but that is frequently associated with heart disease.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

485749

Citation

Isner, J M., et al. "Cardiac Findings in Charcot-Marie-Tooth Disease. a Prospective Study of 68 Patients." Archives of Internal Medicine, vol. 139, no. 10, 1979, pp. 1161-5.
Isner JM, Hawley RJ, Weintraub AM, et al. Cardiac findings in Charcot-Marie-Tooth disease. A prospective study of 68 patients. Arch Intern Med. 1979;139(10):1161-5.
Isner, J. M., Hawley, R. J., Weintraub, A. M., & Engel, W. K. (1979). Cardiac findings in Charcot-Marie-Tooth disease. A prospective study of 68 patients. Archives of Internal Medicine, 139(10), 1161-5.
Isner JM, et al. Cardiac Findings in Charcot-Marie-Tooth Disease. a Prospective Study of 68 Patients. Arch Intern Med. 1979;139(10):1161-5. PubMed PMID: 485749.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cardiac findings in Charcot-Marie-Tooth disease. A prospective study of 68 patients. AU - Isner,J M, AU - Hawley,R J, AU - Weintraub,A M, AU - Engel,W K, PY - 1979/10/1/pubmed PY - 1979/10/1/medline PY - 1979/10/1/entrez SP - 1161 EP - 5 JF - Archives of internal medicine JO - Arch. Intern. Med. VL - 139 IS - 10 N2 - Charcot-Marie-Tooth disease (peroneal muscular atrophy) has been reported to cause cardiac arrthymias and conduction disturbances in association with peripheral muscle atrophy. To establish more accurately the frequency of such cardiac disorders in this disease, 68 patients with Charcot-Marie-Tooth disease were evaluated prospectively for evidence of cardiac involvement. Cardiac findings were limited to five patients with conduction defects, two patients with supraventricular tachycardia, two patients with ischemic heart disease, and 20 with mitral valve prolapse. The frequency of each of the abnormal cardiac findings, with the possibly emalities in the population at large. The low incidence of cardiac involvement in patients with Charcot-Marie-Tooth disease may be helpful in distinguishing this disorder from Friedreich's ataxia, an entity that may mimic Charcot-Marie-Tooth disease but that is frequently associated with heart disease. SN - 0003-9926 UR - https://www.unboundmedicine.com/medline/citation/485749/Cardiac_findings_in_Charcot_Marie_Tooth_disease__A_prospective_study_of_68_patients_ L2 - https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/vol/139/pg/1161 DB - PRIME DP - Unbound Medicine ER -