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Hyperprolactinemia--a review of recent clinical advances.
Arch Intern Med. 1979 Dec; 139(12):1415-9.AI

Abstract

Since the radioimmunoassay for serum prolactin became available eight years ago, prolactin has become a hormone of considerable clinical interest. An elevated serum prolactin concentration is the most frequent hormone marker for pituitary tumors. Secreted in excess, prolactin causes dysfunction of the hypothalamic-pituitary axis, the gonads, and the adrenal cortex. In women, menstrual disturbances, galactorrhea, infertility, and hirsutism result. Impotence, oligospermia, and decreased libido are common in men. These metabolic abnormalities attributed to prolactin excess are corrected when prolactin concentrations are lowered by either medical or surgical therapy. The availability of effective therapy mandates early recognition and proper management of the patient with hyperprolactinemia.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

518224

Citation

Kirby, R W., et al. "Hyperprolactinemia--a Review of Recent Clinical Advances." Archives of Internal Medicine, vol. 139, no. 12, 1979, pp. 1415-9.
Kirby RW, Kotchen TA, Rees ED. Hyperprolactinemia--a review of recent clinical advances. Arch Intern Med. 1979;139(12):1415-9.
Kirby, R. W., Kotchen, T. A., & Rees, E. D. (1979). Hyperprolactinemia--a review of recent clinical advances. Archives of Internal Medicine, 139(12), 1415-9.
Kirby RW, Kotchen TA, Rees ED. Hyperprolactinemia--a Review of Recent Clinical Advances. Arch Intern Med. 1979;139(12):1415-9. PubMed PMID: 518224.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hyperprolactinemia--a review of recent clinical advances. AU - Kirby,R W, AU - Kotchen,T A, AU - Rees,E D, PY - 1979/12/1/pubmed PY - 1979/12/1/medline PY - 1979/12/1/entrez SP - 1415 EP - 9 JF - Archives of internal medicine JO - Arch Intern Med VL - 139 IS - 12 N2 - Since the radioimmunoassay for serum prolactin became available eight years ago, prolactin has become a hormone of considerable clinical interest. An elevated serum prolactin concentration is the most frequent hormone marker for pituitary tumors. Secreted in excess, prolactin causes dysfunction of the hypothalamic-pituitary axis, the gonads, and the adrenal cortex. In women, menstrual disturbances, galactorrhea, infertility, and hirsutism result. Impotence, oligospermia, and decreased libido are common in men. These metabolic abnormalities attributed to prolactin excess are corrected when prolactin concentrations are lowered by either medical or surgical therapy. The availability of effective therapy mandates early recognition and proper management of the patient with hyperprolactinemia. SN - 0003-9926 UR - https://www.unboundmedicine.com/medline/citation/518224/Hyperprolactinemia__a_review_of_recent_clinical_advances_ L2 - https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/vol/139/pg/1415 DB - PRIME DP - Unbound Medicine ER -