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Effect of haemorrhagic hypotension on the circulation of rats with Guérin carcinoma.
Circ Shock. 1979; 6(4):375-84.CS

Abstract

After transplanting Guérin carcinoma in rats the cardiac output (Evans-blue dilution), the distribution of cardiac output (Sapirstein's isotope indicator fractionation technique), the nutritive blood flow of the organs, and their circulatory resistance were investigated in haemorrhagic hypotension (40 or 70 mm Hg). The posthaemorrhagic redistribution of cardiac output in tumor-bearing rats was similar to that found in normal bled animals: the renal and skin fractions of cardiac output decreased and that of the brain, myocardium, and carcass increased. As a result of bleeding the decrease of the tumor fraction of cardiac output was the greatest compared to the other organs. Thus the tumor seems to be the main target organ of the posthaemorrhagic redistribution.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

535140

Citation

Debreczeni, L A., et al. "Effect of Haemorrhagic Hypotension On the Circulation of Rats With Guérin Carcinoma." Circulatory Shock, vol. 6, no. 4, 1979, pp. 375-84.
Debreczeni LA, Farsang C, Takács L. Effect of haemorrhagic hypotension on the circulation of rats with Guérin carcinoma. Circ Shock. 1979;6(4):375-84.
Debreczeni, L. A., Farsang, C., & Takács, L. (1979). Effect of haemorrhagic hypotension on the circulation of rats with Guérin carcinoma. Circulatory Shock, 6(4), 375-84.
Debreczeni LA, Farsang C, Takács L. Effect of Haemorrhagic Hypotension On the Circulation of Rats With Guérin Carcinoma. Circ Shock. 1979;6(4):375-84. PubMed PMID: 535140.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of haemorrhagic hypotension on the circulation of rats with Guérin carcinoma. AU - Debreczeni,L A, AU - Farsang,C, AU - Takács,L, PY - 1979/1/1/pubmed PY - 1979/1/1/medline PY - 1979/1/1/entrez SP - 375 EP - 84 JF - Circulatory shock JO - Circ Shock VL - 6 IS - 4 N2 - After transplanting Guérin carcinoma in rats the cardiac output (Evans-blue dilution), the distribution of cardiac output (Sapirstein's isotope indicator fractionation technique), the nutritive blood flow of the organs, and their circulatory resistance were investigated in haemorrhagic hypotension (40 or 70 mm Hg). The posthaemorrhagic redistribution of cardiac output in tumor-bearing rats was similar to that found in normal bled animals: the renal and skin fractions of cardiac output decreased and that of the brain, myocardium, and carcass increased. As a result of bleeding the decrease of the tumor fraction of cardiac output was the greatest compared to the other organs. Thus the tumor seems to be the main target organ of the posthaemorrhagic redistribution. SN - 0092-6213 UR - https://www.unboundmedicine.com/medline/citation/535140/Effect_of_haemorrhagic_hypotension_on_the_circulation_of_rats_with_Guérin_carcinoma_ L2 - https://antibodies.cancer.gov/detail/CPTC-HLA-B-1 DB - PRIME DP - Unbound Medicine ER -