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Marihuana: studies on the disposition and metabolism of delta-9-tetrahydrocannabinol in man.
Science. 1970 Dec 18; 170(3964):1320-2.Sci

Abstract

Delta(9)-Tetrahydrocannabinol (the major active component of marihuana) administered intravenously to normal human volunteers persists in plasma for more than 3 days (t(1/2) = 56 hours). Its metabolites appear in plasma within 10 minutes after administration and persist along with the precursor compound. Delta(9)-Tetrahydrocannabinol is completely metabolized in man, and the radioactive metabolites are excreted in urine and feces for more than 8 days.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

5479011

Citation

Lemberger, L, et al. "Marihuana: Studies On the Disposition and Metabolism of Delta-9-tetrahydrocannabinol in Man." Science (New York, N.Y.), vol. 170, no. 3964, 1970, pp. 1320-2.
Lemberger L, Silberstein SD, Axelrod J, et al. Marihuana: studies on the disposition and metabolism of delta-9-tetrahydrocannabinol in man. Science. 1970;170(3964):1320-2.
Lemberger, L., Silberstein, S. D., Axelrod, J., & Kopin, I. J. (1970). Marihuana: studies on the disposition and metabolism of delta-9-tetrahydrocannabinol in man. Science (New York, N.Y.), 170(3964), 1320-2.
Lemberger L, et al. Marihuana: Studies On the Disposition and Metabolism of Delta-9-tetrahydrocannabinol in Man. Science. 1970 Dec 18;170(3964):1320-2. PubMed PMID: 5479011.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Marihuana: studies on the disposition and metabolism of delta-9-tetrahydrocannabinol in man. AU - Lemberger,L, AU - Silberstein,S D, AU - Axelrod,J, AU - Kopin,I J, PY - 1970/12/18/pubmed PY - 1970/12/18/medline PY - 1970/12/18/entrez SP - 1320 EP - 2 JF - Science (New York, N.Y.) JO - Science VL - 170 IS - 3964 N2 - Delta(9)-Tetrahydrocannabinol (the major active component of marihuana) administered intravenously to normal human volunteers persists in plasma for more than 3 days (t(1/2) = 56 hours). Its metabolites appear in plasma within 10 minutes after administration and persist along with the precursor compound. Delta(9)-Tetrahydrocannabinol is completely metabolized in man, and the radioactive metabolites are excreted in urine and feces for more than 8 days. SN - 0036-8075 UR - https://www.unboundmedicine.com/medline/citation/5479011/Marihuana:_studies_on_the_disposition_and_metabolism_of_delta_9_tetrahydrocannabinol_in_man_ L2 - https://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=5479011 DB - PRIME DP - Unbound Medicine ER -