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Thymidine photoproducts of non-cyclobutane type as a crucial event in the conformation of UV-irradiated DNA.
Acta Biol Med Ger. 1979; 38(9):1233-7.AB

Abstract

The UV-light induced conformational effects in deoxyoligonucleotides and polynucleotides have been analyzed by CD measurements and isolation of the photoproducts. The results demonstrate that the essential photoproduct formed on irradiation of thymidylyl-thymidine at 254 nm is of non-cyclobutane type and may be correlated to the primary photoproduct formed in DNAs at low doses Formation of thymine dimers of cyclobutane-type structure appears to be a secondary product generated by treatment with formic acid.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

550665

Citation

Lang, H, et al. "Thymidine Photoproducts of Non-cyclobutane Type as a Crucial Event in the Conformation of UV-irradiated DNA." Acta Biologica Et Medica Germanica, vol. 38, no. 9, 1979, pp. 1233-7.
Lang H, Birch-Hirschfeld E, Zimmer C. Thymidine photoproducts of non-cyclobutane type as a crucial event in the conformation of UV-irradiated DNA. Acta Biol Med Ger. 1979;38(9):1233-7.
Lang, H., Birch-Hirschfeld, E., & Zimmer, C. (1979). Thymidine photoproducts of non-cyclobutane type as a crucial event in the conformation of UV-irradiated DNA. Acta Biologica Et Medica Germanica, 38(9), 1233-7.
Lang H, Birch-Hirschfeld E, Zimmer C. Thymidine Photoproducts of Non-cyclobutane Type as a Crucial Event in the Conformation of UV-irradiated DNA. Acta Biol Med Ger. 1979;38(9):1233-7. PubMed PMID: 550665.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Thymidine photoproducts of non-cyclobutane type as a crucial event in the conformation of UV-irradiated DNA. AU - Lang,H, AU - Birch-Hirschfeld,E, AU - Zimmer,C, PY - 1979/1/1/pubmed PY - 1979/1/1/medline PY - 1979/1/1/entrez SP - 1233 EP - 7 JF - Acta biologica et medica Germanica JO - Acta Biol. Med. Ger. VL - 38 IS - 9 N2 - The UV-light induced conformational effects in deoxyoligonucleotides and polynucleotides have been analyzed by CD measurements and isolation of the photoproducts. The results demonstrate that the essential photoproduct formed on irradiation of thymidylyl-thymidine at 254 nm is of non-cyclobutane type and may be correlated to the primary photoproduct formed in DNAs at low doses Formation of thymine dimers of cyclobutane-type structure appears to be a secondary product generated by treatment with formic acid. SN - 0001-5318 UR - https://www.unboundmedicine.com/medline/citation/550665/Thymidine_photoproducts_of_non_cyclobutane_type_as_a_crucial_event_in_the_conformation_of_UV_irradiated_DNA_ DB - PRIME DP - Unbound Medicine ER -