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Intrinsic-factor antibody and absorption of vtiamin B12 in pernicious anaemia.
Br Med J. 1971 Jan 02; 1(5739):25-6.BM

Abstract

The mean urinary excretion in a vitamin-B(12) absorption (Schilling) test in control subjects was 19.2% and in pernicious anaemia when given with additional intrinsic factor was as follows: no intrinsic-factor antibodies demonstrable 19.3%, antibodies in serum only 14.4%, antibodies in gastric juice only 11.1%, and antibodies in both serum and gastric juice 8.4%. It is concluded that intrinsic-factor antibody exerts an adverse effect on vitamin-B(12) absorption in most patients with pernicious anaemia.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

5539138

Citation

Rose, M S., and I Chanarin. "Intrinsic-factor Antibody and Absorption of Vtiamin B12 in Pernicious Anaemia." British Medical Journal, vol. 1, no. 5739, 1971, pp. 25-6.
Rose MS, Chanarin I. Intrinsic-factor antibody and absorption of vtiamin B12 in pernicious anaemia. Br Med J. 1971;1(5739):25-6.
Rose, M. S., & Chanarin, I. (1971). Intrinsic-factor antibody and absorption of vtiamin B12 in pernicious anaemia. British Medical Journal, 1(5739), 25-6.
Rose MS, Chanarin I. Intrinsic-factor Antibody and Absorption of Vtiamin B12 in Pernicious Anaemia. Br Med J. 1971 Jan 2;1(5739):25-6. PubMed PMID: 5539138.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intrinsic-factor antibody and absorption of vtiamin B12 in pernicious anaemia. AU - Rose,M S, AU - Chanarin,I, PY - 1971/1/2/pubmed PY - 1971/1/2/medline PY - 1971/1/2/entrez SP - 25 EP - 6 JF - British medical journal JO - Br Med J VL - 1 IS - 5739 N2 - The mean urinary excretion in a vitamin-B(12) absorption (Schilling) test in control subjects was 19.2% and in pernicious anaemia when given with additional intrinsic factor was as follows: no intrinsic-factor antibodies demonstrable 19.3%, antibodies in serum only 14.4%, antibodies in gastric juice only 11.1%, and antibodies in both serum and gastric juice 8.4%. It is concluded that intrinsic-factor antibody exerts an adverse effect on vitamin-B(12) absorption in most patients with pernicious anaemia. SN - 0007-1447 UR - https://www.unboundmedicine.com/medline/citation/5539138/Intrinsic_factor_antibody_and_absorption_of_vtiamin_B12_in_pernicious_anaemia_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/5539138/ DB - PRIME DP - Unbound Medicine ER -