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Zinc protoporphyrin level in blood determined by a portable hematofluorometer: a screening device for lead poisoning.
J Lab Clin Med. 1977 Apr; 89(4):712-23.JL

Abstract

An inexpensive portable fluorometer has been designed which can be used to determine the concentration of zinc protoporphyrin (ZPP) in a drop of unprocessed blood deposited on a disposable glass slide. No volume measurement of the blood sample need be made. The instrument displays the ZPP level in micrograms per deciliter of blood accurately and reproducibly, automatically calibrating each determination by comparing the blood fluorescence with that of a stable dye. The instrument, which we call a hematofluorometer, is ideally suited for use in primary screening for childhood and occupational lead intoxication. It can be used by public health personnel after a few minutes of instruction. Comparisons of ZPP levels obtained with the use of the hematofluorometer with erythrocyte protoporphyrin levels obtained using accepted extraction methods are presented.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

557519

Citation

Blumberg, W E., et al. "Zinc Protoporphyrin Level in Blood Determined By a Portable Hematofluorometer: a Screening Device for Lead Poisoning." The Journal of Laboratory and Clinical Medicine, vol. 89, no. 4, 1977, pp. 712-23.
Blumberg WE, Eisinger J, Lamola AA, et al. Zinc protoporphyrin level in blood determined by a portable hematofluorometer: a screening device for lead poisoning. J Lab Clin Med. 1977;89(4):712-23.
Blumberg, W. E., Eisinger, J., Lamola, A. A., & Zuckerman, D. M. (1977). Zinc protoporphyrin level in blood determined by a portable hematofluorometer: a screening device for lead poisoning. The Journal of Laboratory and Clinical Medicine, 89(4), 712-23.
Blumberg WE, et al. Zinc Protoporphyrin Level in Blood Determined By a Portable Hematofluorometer: a Screening Device for Lead Poisoning. J Lab Clin Med. 1977;89(4):712-23. PubMed PMID: 557519.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Zinc protoporphyrin level in blood determined by a portable hematofluorometer: a screening device for lead poisoning. AU - Blumberg,W E, AU - Eisinger,J, AU - Lamola,A A, AU - Zuckerman,D M, PY - 1977/4/1/pubmed PY - 1977/4/1/medline PY - 1977/4/1/entrez SP - 712 EP - 23 JF - The Journal of laboratory and clinical medicine JO - J Lab Clin Med VL - 89 IS - 4 N2 - An inexpensive portable fluorometer has been designed which can be used to determine the concentration of zinc protoporphyrin (ZPP) in a drop of unprocessed blood deposited on a disposable glass slide. No volume measurement of the blood sample need be made. The instrument displays the ZPP level in micrograms per deciliter of blood accurately and reproducibly, automatically calibrating each determination by comparing the blood fluorescence with that of a stable dye. The instrument, which we call a hematofluorometer, is ideally suited for use in primary screening for childhood and occupational lead intoxication. It can be used by public health personnel after a few minutes of instruction. Comparisons of ZPP levels obtained with the use of the hematofluorometer with erythrocyte protoporphyrin levels obtained using accepted extraction methods are presented. SN - 0022-2143 UR - https://www.unboundmedicine.com/medline/citation/557519/Zinc_protoporphyrin_level_in_blood_determined_by_a_portable_hematofluorometer:_a_screening_device_for_lead_poisoning_ DB - PRIME DP - Unbound Medicine ER -