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Kayser-Fleischer-like rings in patients without Wilson's disease.
Gastroenterology. 1977 Jun; 72(6):1331-5.G

Abstract

Three patients, one with cryptogenic cirrhosis, one with active chronic hepatitis and one with neonatal hepatitis, were found to have corneal pigmentation rings indistinguishable from early Kayser-Fleischer rings on slit lamp examination. They did not have the clinical features of Wilson's disease and their serum copper and ceruloplasmin concentrations were normal. Urinary copper excretion rates and hepatic concentrations were only slightly raised but were below the range found in symptomatic Wilson's disease. It is concluded that the Kayser-Fleischer ring would no longer be considered as pathognomonic of Wilson's disease.

Authors

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Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

558126

Citation

Frommer, D, et al. "Kayser-Fleischer-like Rings in Patients Without Wilson's Disease." Gastroenterology, vol. 72, no. 6, 1977, pp. 1331-5.
Frommer D, Morris J, Sherlock S, et al. Kayser-Fleischer-like rings in patients without Wilson's disease. Gastroenterology. 1977;72(6):1331-5.
Frommer, D., Morris, J., Sherlock, S., Abrams, J., & Newman, S. (1977). Kayser-Fleischer-like rings in patients without Wilson's disease. Gastroenterology, 72(6), 1331-5.
Frommer D, et al. Kayser-Fleischer-like Rings in Patients Without Wilson's Disease. Gastroenterology. 1977;72(6):1331-5. PubMed PMID: 558126.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Kayser-Fleischer-like rings in patients without Wilson's disease. AU - Frommer,D, AU - Morris,J, AU - Sherlock,S, AU - Abrams,J, AU - Newman,S, PY - 1977/6/1/pubmed PY - 1977/6/1/medline PY - 1977/6/1/entrez SP - 1331 EP - 5 JF - Gastroenterology JO - Gastroenterology VL - 72 IS - 6 N2 - Three patients, one with cryptogenic cirrhosis, one with active chronic hepatitis and one with neonatal hepatitis, were found to have corneal pigmentation rings indistinguishable from early Kayser-Fleischer rings on slit lamp examination. They did not have the clinical features of Wilson's disease and their serum copper and ceruloplasmin concentrations were normal. Urinary copper excretion rates and hepatic concentrations were only slightly raised but were below the range found in symptomatic Wilson's disease. It is concluded that the Kayser-Fleischer ring would no longer be considered as pathognomonic of Wilson's disease. SN - 0016-5085 UR - https://www.unboundmedicine.com/medline/citation/558126/Kayser_Fleischer_like_rings_in_patients_without_Wilson's_disease_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0016508577001632 DB - PRIME DP - Unbound Medicine ER -