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Antineoplastic agents. 52. Baileya multiradiata.
Lloydia. 1978 Jan-Feb; 41(1):29-36.L

Abstract

The desert-marigold Baileya multiradiata Harv. and Gray (Compositae) has been found to produce a series of sesquiterpenes that markedly inhibit growth of the murine lymphocytic leukemia P388 and the corresponding in vitro cell line. Separation guided by bioassay led to the isolation of baileyin (1), fastigilins B and C (3a and 2a), radiatin (3b), pleniradin (4a), and the new pseudoguaianolide multiradiatin (2b). The most significant antitumor activity was displayed by fastigilin C (2a) and radiation (3b).

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

565454

Citation

Pettit, G R., et al. "Antineoplastic Agents. 52. Baileya Multiradiata." Lloydia, vol. 41, no. 1, 1978, pp. 29-36.
Pettit GR, Herald CL, Judd GF, et al. Antineoplastic agents. 52. Baileya multiradiata. Lloydia. 1978;41(1):29-36.
Pettit, G. R., Herald, C. L., Judd, G. F., Bolliger, G., Vanell, L. D., Lehto, E., & Pase, C. P. (1978). Antineoplastic agents. 52. Baileya multiradiata. Lloydia, 41(1), 29-36.
Pettit GR, et al. Antineoplastic Agents. 52. Baileya Multiradiata. Lloydia. 1978 Jan-Feb;41(1):29-36. PubMed PMID: 565454.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antineoplastic agents. 52. Baileya multiradiata. AU - Pettit,G R, AU - Herald,C L, AU - Judd,G F, AU - Bolliger,G, AU - Vanell,L D, AU - Lehto,E, AU - Pase,C P, PY - 1978/1/1/pubmed PY - 1978/1/1/medline PY - 1978/1/1/entrez SP - 29 EP - 36 JF - Lloydia JO - Lloydia VL - 41 IS - 1 N2 - The desert-marigold Baileya multiradiata Harv. and Gray (Compositae) has been found to produce a series of sesquiterpenes that markedly inhibit growth of the murine lymphocytic leukemia P388 and the corresponding in vitro cell line. Separation guided by bioassay led to the isolation of baileyin (1), fastigilins B and C (3a and 2a), radiatin (3b), pleniradin (4a), and the new pseudoguaianolide multiradiatin (2b). The most significant antitumor activity was displayed by fastigilin C (2a) and radiation (3b). SN - 0024-5461 UR - https://www.unboundmedicine.com/medline/citation/565454/Antineoplastic_agents__52__Baileya_multiradiata_ L2 - https://medlineplus.gov/cancerchemotherapy.html DB - PRIME DP - Unbound Medicine ER -