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Clinically suspected deep venous thrombosis of the lower extremities. A comparison of venography, impedance plethysmography, and radiolabeled fibrinogen.
JAMA. 1977 May 16; 237(20):2195-8.JAMA

Abstract

To define the utility of new diagnostic approaches in patients with clinically suspected deep venous thrombosis of the lower extremities, 42 legs of 33 patients were studied by fibrinogen labeled with radioactivie iodine (125I) impedance plethysmography (IPG), and contrast venography. The clinical diagnosis was confirmed in approximately two thirds of the legs and patients. In venogram-positive legs, fibrinogen 125I was positive in 70%, IPG in 61%, and one of the two in 78%. In venogram-negative legs, fibrinogen 125I was positive in four (21%) and IPG was negative in all. It was found that the size, age, and location of the thrombus, collateral vein development, heparin sodium therapy, and technical-interpretive choices can influence both IPG and fibrinogen 125I results. The data demonstrate that the fibrinogen 125I and IPG procedures can assist physicians in the diagnosis of clinically suspected deep venous thrombosis of the lower extremities.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

576903

Citation

Moser, K M., et al. "Clinically Suspected Deep Venous Thrombosis of the Lower Extremities. a Comparison of Venography, Impedance Plethysmography, and Radiolabeled Fibrinogen." JAMA, vol. 237, no. 20, 1977, pp. 2195-8.
Moser KM, Brach BB, Dolan GF. Clinically suspected deep venous thrombosis of the lower extremities. A comparison of venography, impedance plethysmography, and radiolabeled fibrinogen. JAMA. 1977;237(20):2195-8.
Moser, K. M., Brach, B. B., & Dolan, G. F. (1977). Clinically suspected deep venous thrombosis of the lower extremities. A comparison of venography, impedance plethysmography, and radiolabeled fibrinogen. JAMA, 237(20), 2195-8.
Moser KM, Brach BB, Dolan GF. Clinically Suspected Deep Venous Thrombosis of the Lower Extremities. a Comparison of Venography, Impedance Plethysmography, and Radiolabeled Fibrinogen. JAMA. 1977 May 16;237(20):2195-8. PubMed PMID: 576903.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinically suspected deep venous thrombosis of the lower extremities. A comparison of venography, impedance plethysmography, and radiolabeled fibrinogen. AU - Moser,K M, AU - Brach,B B, AU - Dolan,G F, PY - 1977/5/16/pubmed PY - 1977/5/16/medline PY - 1977/5/16/entrez SP - 2195 EP - 8 JF - JAMA JO - JAMA VL - 237 IS - 20 N2 - To define the utility of new diagnostic approaches in patients with clinically suspected deep venous thrombosis of the lower extremities, 42 legs of 33 patients were studied by fibrinogen labeled with radioactivie iodine (125I) impedance plethysmography (IPG), and contrast venography. The clinical diagnosis was confirmed in approximately two thirds of the legs and patients. In venogram-positive legs, fibrinogen 125I was positive in 70%, IPG in 61%, and one of the two in 78%. In venogram-negative legs, fibrinogen 125I was positive in four (21%) and IPG was negative in all. It was found that the size, age, and location of the thrombus, collateral vein development, heparin sodium therapy, and technical-interpretive choices can influence both IPG and fibrinogen 125I results. The data demonstrate that the fibrinogen 125I and IPG procedures can assist physicians in the diagnosis of clinically suspected deep venous thrombosis of the lower extremities. SN - 0098-7484 UR - https://www.unboundmedicine.com/medline/citation/576903/Clinically_suspected_deep_venous_thrombosis_of_the_lower_extremities__A_comparison_of_venography_impedance_plethysmography_and_radiolabeled_fibrinogen_ L2 - https://jamanetwork.com/journals/jama/fullarticle/vol/237/pg/2195 DB - PRIME DP - Unbound Medicine ER -