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Thrombotic thrombocytopenic purpura in a child with Alexander's disease.
Arch Pathol Lab Med. 1977 Dec; 101(12):655-7.AP

Abstract

Thrombocytopenic purpura developed in a 14-year-old boy with Alexander's disease; he died. The proximity of Rosenthal fibers to small vessels in the brain, the presence of perivascular lymphocytes in the brain, and the presence of complement in renal arterioles suggest that the Rosenthal fibers could have injured the endothelium-basement membrane resulting in an immune response triggering the thrombotic thrombocytopenic purpura.

Authors

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Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

579308

Citation

Rankin, W E., et al. "Thrombotic Thrombocytopenic Purpura in a Child With Alexander's Disease." Archives of Pathology & Laboratory Medicine, vol. 101, no. 12, 1977, pp. 655-7.
Rankin WE, Hart MN, Weisenburger DD. Thrombotic thrombocytopenic purpura in a child with Alexander's disease. Arch Pathol Lab Med. 1977;101(12):655-7.
Rankin, W. E., Hart, M. N., & Weisenburger, D. D. (1977). Thrombotic thrombocytopenic purpura in a child with Alexander's disease. Archives of Pathology & Laboratory Medicine, 101(12), 655-7.
Rankin WE, Hart MN, Weisenburger DD. Thrombotic Thrombocytopenic Purpura in a Child With Alexander's Disease. Arch Pathol Lab Med. 1977;101(12):655-7. PubMed PMID: 579308.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Thrombotic thrombocytopenic purpura in a child with Alexander's disease. AU - Rankin,W E, AU - Hart,M N, AU - Weisenburger,D D, PY - 1977/12/1/pubmed PY - 1977/12/1/medline PY - 1977/12/1/entrez SP - 655 EP - 7 JF - Archives of pathology & laboratory medicine JO - Arch. Pathol. Lab. Med. VL - 101 IS - 12 N2 - Thrombocytopenic purpura developed in a 14-year-old boy with Alexander's disease; he died. The proximity of Rosenthal fibers to small vessels in the brain, the presence of perivascular lymphocytes in the brain, and the presence of complement in renal arterioles suggest that the Rosenthal fibers could have injured the endothelium-basement membrane resulting in an immune response triggering the thrombotic thrombocytopenic purpura. SN - 0003-9985 UR - https://www.unboundmedicine.com/medline/citation/579308/Thrombotic_thrombocytopenic_purpura_in_a_child_with_Alexander's_disease_ DB - PRIME DP - Unbound Medicine ER -