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Subacute sclerosing leukoencephalitis: ultrastructure of intranuclear and intracytoplasmic inclusions.
Science. 1966 Nov 18; 154(3751):899-901.Sci

Abstract

Intranuclear inclusions found in glial cells of two cases of subacute sclerosing leukoencephalitis have been examined in the electron microscope. The inclusions are composed of filamentous tubules 170 to 230 angstroms in diameter, which bear a general resemblance to the intranuclear structures observed in cells infected with measles virus. This finding provides further suggestive evidence that a virus may be involved in the pathogenesis of subacute sclerosing leukoencephalitis.

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Publisher Full Text

Authors

Tellez-Negal I
No affiliation info available
Harter DH
No affiliation info available

MeSH

CerebellumCerebral CortexDiffuse Cerebral Sclerosis of SchilderEncephalitisFrontal LobeHumansInclusion Bodies, ViralMicroscopy, ElectronNeurogliaVirus Diseases

Pub Type(s)

Journal Article

Language

eng

PubMed ID

6003536

Citation

Tellez-Negal, I, and D H. Harter. "Subacute Sclerosing Leukoencephalitis: Ultrastructure of Intranuclear and Intracytoplasmic Inclusions." Science (New York, N.Y.), vol. 154, no. 3751, 1966, pp. 899-901.
Tellez-Negal I, Harter DH. Subacute sclerosing leukoencephalitis: ultrastructure of intranuclear and intracytoplasmic inclusions. Science. 1966;154(3751):899-901.
Tellez-Negal, I., & Harter, D. H. (1966). Subacute sclerosing leukoencephalitis: ultrastructure of intranuclear and intracytoplasmic inclusions. Science (New York, N.Y.), 154(3751), 899-901.
Tellez-Negal I, Harter DH. Subacute Sclerosing Leukoencephalitis: Ultrastructure of Intranuclear and Intracytoplasmic Inclusions. Science. 1966 Nov 18;154(3751):899-901. PubMed PMID: 6003536.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Subacute sclerosing leukoencephalitis: ultrastructure of intranuclear and intracytoplasmic inclusions. AU - Tellez-Negal,I, AU - Harter,D H, PY - 1966/11/18/pubmed PY - 1966/11/18/medline PY - 1966/11/18/entrez SP - 899 EP - 901 JF - Science (New York, N.Y.) JO - Science VL - 154 IS - 3751 N2 - Intranuclear inclusions found in glial cells of two cases of subacute sclerosing leukoencephalitis have been examined in the electron microscope. The inclusions are composed of filamentous tubules 170 to 230 angstroms in diameter, which bear a general resemblance to the intranuclear structures observed in cells infected with measles virus. This finding provides further suggestive evidence that a virus may be involved in the pathogenesis of subacute sclerosing leukoencephalitis. SN - 0036-8075 UR - https://www.unboundmedicine.com/medline/citation/6003536/Subacute_sclerosing_leukoencephalitis:_ultrastructure_of_intranuclear_and_intracytoplasmic_inclusions_ L2 - https://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=6003536 DB - PRIME DP - Unbound Medicine ER -