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Acanthosis nigricans maligna. Clinical and virological investigations.
Dermatologica. 1984; 168(6):265-72.D

Abstract

2 cases of acanthosis nigricans associated with an adenocarcinoma (signet ring cell carcinoma) of the stomach and a metastasizing small-cell carcinoma of unknown origin are reported. In both cases the skin lesions preceded the diagnosis of the carcinoma by months and acanthosis nigricans maligna was suspected by onset and localization of the dermatosis. There was no evidence of a papillomavirus etiology of the warty skin lesions. Virus particles could not be demonstrated either in ultrathin sections or in buffer extracts. Virus-specific DNA was not detectable after CsCL-ethidium bromide gradient centrifugation and cellular DNA did not hybridize under stringent or relaxed conditions with 32P-labelled human papillomavirus 6 or human papillomavirus 8 DNA.

Authors

Gross G
No affiliation info available
Pfister H
No affiliation info available
Hellenthal B
No affiliation info available
Hagedorn M
No affiliation info available

MeSH

Acanthosis NigricansAdenocarcinoma, MucinousAdultAnimalsCarcinoma, Small CellDNA, ViralFemaleHumansLung NeoplasmsLymphatic MetastasisMaleMicroscopy, ElectronMiddle AgedPapillomaviridaeParaneoplastic SyndromesStomach NeoplasmsTumor Virus Infections

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

6086413

Citation

Gross, G, et al. "Acanthosis Nigricans Maligna. Clinical and Virological Investigations." Dermatologica, vol. 168, no. 6, 1984, pp. 265-72.
Gross G, Pfister H, Hellenthal B, et al. Acanthosis nigricans maligna. Clinical and virological investigations. Dermatologica. 1984;168(6):265-72.
Gross, G., Pfister, H., Hellenthal, B., & Hagedorn, M. (1984). Acanthosis nigricans maligna. Clinical and virological investigations. Dermatologica, 168(6), 265-72.
Gross G, et al. Acanthosis Nigricans Maligna. Clinical and Virological Investigations. Dermatologica. 1984;168(6):265-72. PubMed PMID: 6086413.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acanthosis nigricans maligna. Clinical and virological investigations. AU - Gross,G, AU - Pfister,H, AU - Hellenthal,B, AU - Hagedorn,M, PY - 1984/1/1/pubmed PY - 1984/1/1/medline PY - 1984/1/1/entrez SP - 265 EP - 72 JF - Dermatologica JO - Dermatologica VL - 168 IS - 6 N2 - 2 cases of acanthosis nigricans associated with an adenocarcinoma (signet ring cell carcinoma) of the stomach and a metastasizing small-cell carcinoma of unknown origin are reported. In both cases the skin lesions preceded the diagnosis of the carcinoma by months and acanthosis nigricans maligna was suspected by onset and localization of the dermatosis. There was no evidence of a papillomavirus etiology of the warty skin lesions. Virus particles could not be demonstrated either in ultrathin sections or in buffer extracts. Virus-specific DNA was not detectable after CsCL-ethidium bromide gradient centrifugation and cellular DNA did not hybridize under stringent or relaxed conditions with 32P-labelled human papillomavirus 6 or human papillomavirus 8 DNA. SN - 0011-9075 UR - https://www.unboundmedicine.com/medline/citation/6086413/Acanthosis_nigricans_maligna__Clinical_and_virological_investigations_ L2 - http://www.diseaseinfosearch.org/result/90 DB - PRIME DP - Unbound Medicine ER -