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[Peripheral nerve lesions in chloroquine-induced neuromyopathies].
Ann Pathol. 1984 Sep-Nov; 4(4):289-95.AP

Abstract

Two cases of chloroquine-induced neuromyopathy are described. The clinical picture is a proximal weakness of lower limbs in one case, and a sensory peripheral neuropathy in the other. Vacuolar changes were not found in muscle biopsies, but electron microscopic studies revealed characteristic dense and lamellated inclusion bodies in muscle fibers and endothelial cells. Sural nerve biopsies were performed in each case. There was a severe loss of myelinated fibers in one. Dense and lamellated inclusions were found in schwann cells, perineural and endothelial cells. In a literature review, only one case with sural nerve biopsy is found in human pathology of chloroquine neuromyopathy.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

fre

PubMed ID

6095877

Citation

Pagès, M, and A M. Pagès. "[Peripheral Nerve Lesions in Chloroquine-induced Neuromyopathies]." Annales De Pathologie, vol. 4, no. 4, 1984, pp. 289-95.
Pagès M, Pagès AM. [Peripheral nerve lesions in chloroquine-induced neuromyopathies]. Ann Pathol. 1984;4(4):289-95.
Pagès, M., & Pagès, A. M. (1984). [Peripheral nerve lesions in chloroquine-induced neuromyopathies]. Annales De Pathologie, 4(4), 289-95.
Pagès M, Pagès AM. [Peripheral Nerve Lesions in Chloroquine-induced Neuromyopathies]. Ann Pathol. 1984 Sep-Nov;4(4):289-95. PubMed PMID: 6095877.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Peripheral nerve lesions in chloroquine-induced neuromyopathies]. AU - Pagès,M, AU - Pagès,A M, PY - 1984/9/1/pubmed PY - 1984/9/1/medline PY - 1984/9/1/entrez SP - 289 EP - 95 JF - Annales de pathologie JO - Ann Pathol VL - 4 IS - 4 N2 - Two cases of chloroquine-induced neuromyopathy are described. The clinical picture is a proximal weakness of lower limbs in one case, and a sensory peripheral neuropathy in the other. Vacuolar changes were not found in muscle biopsies, but electron microscopic studies revealed characteristic dense and lamellated inclusion bodies in muscle fibers and endothelial cells. Sural nerve biopsies were performed in each case. There was a severe loss of myelinated fibers in one. Dense and lamellated inclusions were found in schwann cells, perineural and endothelial cells. In a literature review, only one case with sural nerve biopsy is found in human pathology of chloroquine neuromyopathy. SN - 0242-6498 UR - https://www.unboundmedicine.com/medline/citation/6095877/[Peripheral_nerve_lesions_in_chloroquine_induced_neuromyopathies]_ L2 - https://medlineplus.gov/neuromusculardisorders.html DB - PRIME DP - Unbound Medicine ER -