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[Lack of viral persistence in 2 Cebus sp].
Rev Argent Microbiol. 1984; 16(2):107-10.RA

Abstract

Two Cebus sp surviving acute Junin virus infection, one after intramuscular inoculation with pathogenic XJ and the other after intracerebral inoculation with XJ Clone 3, failed to exhibit persistent infection. Although treatment with immunosuppressive drugs was carried out, no Junin virus was detected in blood or organs in spite of blind passages in mice for the former as well as cocultivation with permissive Vero cells for the latter. Viremia was also ruled out by immunofluorescence on BHK/21 cell culture. These findings correlate with the lack of long-lasting virus in blood observed in humans following the acute phase of Argentine Hemorrhagic Fever.

Authors+Show Affiliations

Oubiña JR
Cátedra de Microbiología, Parasitología e Inmunología, Facultad Medicina, Universidad de Buenos Aires, Argentina.
Videla CM
No affiliation info available
Carballal G
No affiliation info available

MeSH

AnimalsAntigens, ViralArenaviridaeArenaviruses, New WorldCebidaeCebusConvalescenceFemaleHemorrhagic Fever, AmericanImmunosuppressive AgentsMaleMice

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

spa

PubMed ID

6101036

Citation

Oubiña, J R., et al. "[Lack of Viral Persistence in 2 Cebus Sp]." Revista Argentina De Microbiologia, vol. 16, no. 2, 1984, pp. 107-10.
Oubiña JR, Videla CM, Carballal G. [Lack of viral persistence in 2 Cebus sp]. Rev Argent Microbiol. 1984;16(2):107-10.
Oubiña, J. R., Videla, C. M., & Carballal, G. (1984). [Lack of viral persistence in 2 Cebus sp]. Revista Argentina De Microbiologia, 16(2), 107-10.
Oubiña JR, Videla CM, Carballal G. [Lack of Viral Persistence in 2 Cebus Sp]. Rev Argent Microbiol. 1984;16(2):107-10. PubMed PMID: 6101036.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Lack of viral persistence in 2 Cebus sp]. AU - Oubiña,J R, AU - Videla,C M, AU - Carballal,G, PY - 1984/1/1/pubmed PY - 1984/1/1/medline PY - 1984/1/1/entrez SP - 107 EP - 10 JF - Revista Argentina de microbiologia JO - Rev Argent Microbiol VL - 16 IS - 2 N2 - Two Cebus sp surviving acute Junin virus infection, one after intramuscular inoculation with pathogenic XJ and the other after intracerebral inoculation with XJ Clone 3, failed to exhibit persistent infection. Although treatment with immunosuppressive drugs was carried out, no Junin virus was detected in blood or organs in spite of blind passages in mice for the former as well as cocultivation with permissive Vero cells for the latter. Viremia was also ruled out by immunofluorescence on BHK/21 cell culture. These findings correlate with the lack of long-lasting virus in blood observed in humans following the acute phase of Argentine Hemorrhagic Fever. SN - 0325-7541 UR - https://www.unboundmedicine.com/medline/citation/6101036/[Lack_of_viral_persistence_in_2_Cebus_sp]_ DB - PRIME DP - Unbound Medicine ER -