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An indirect haemagglutination test for demonstration of gonococcal antibodies using gonococcal pili as antigen. II. Serological investigation of patients attending a dermato-venereological outpatients clinic in Copenhagen.
Acta Pathol Microbiol Scand C. 1980 Jun; 88(3):155-62.AP

Abstract

A total of 1223 serum specimens were obtained from 649 consecutive patients attending a dermatovenereological out-patient clinic in Copenhagen with a request for venereal disease control. The sera were examined for gonococcal antibodies by both a gonococcal complement fixation test (GCF) and an indirect haemagglutination test using gonococcal pili as antigens (IHA). The diagnosis of current gonococcal infection in 28 per cent of the patients was based on positive culture for Neisseria gonorrhoeae from one or more of the following sites: urethra, rectum and fauces in all patients, and/or cervix in female patients. The specificity, sensitivity and predictive values of positive and negative test results were calculated for the various groups of patients on the assumption that all positive results, both in patients without gonorrhoea but with a previous gonococcal infection and in patients without known current or previous infection, were false positives. The following values were found: Sensitivity: IHA 45-100%, GCF 6-29%. Specificity: IHA 65-89%, GCF 97-100%. Predictive value of positive test result: IHA 43-74%, GCF 69-100%. Predictive value of negative test result: IHA 78-100%, GCF 61-85%.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

6108675

Citation

Reimann, K, et al. "An Indirect Haemagglutination Test for Demonstration of Gonococcal Antibodies Using Gonococcal Pili as Antigen. II. Serological Investigation of Patients Attending a Dermato-venereological Outpatients Clinic in Copenhagen." Acta Pathologica Et Microbiologica Scandinavica. Section C, Immunology, vol. 88, no. 3, 1980, pp. 155-62.
Reimann K, Lind I, Andersen KE. An indirect haemagglutination test for demonstration of gonococcal antibodies using gonococcal pili as antigen. II. Serological investigation of patients attending a dermato-venereological outpatients clinic in Copenhagen. Acta Pathol Microbiol Scand C. 1980;88(3):155-62.
Reimann, K., Lind, I., & Andersen, K. E. (1980). An indirect haemagglutination test for demonstration of gonococcal antibodies using gonococcal pili as antigen. II. Serological investigation of patients attending a dermato-venereological outpatients clinic in Copenhagen. Acta Pathologica Et Microbiologica Scandinavica. Section C, Immunology, 88(3), 155-62.
Reimann K, Lind I, Andersen KE. An Indirect Haemagglutination Test for Demonstration of Gonococcal Antibodies Using Gonococcal Pili as Antigen. II. Serological Investigation of Patients Attending a Dermato-venereological Outpatients Clinic in Copenhagen. Acta Pathol Microbiol Scand C. 1980;88(3):155-62. PubMed PMID: 6108675.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An indirect haemagglutination test for demonstration of gonococcal antibodies using gonococcal pili as antigen. II. Serological investigation of patients attending a dermato-venereological outpatients clinic in Copenhagen. AU - Reimann,K, AU - Lind,I, AU - Andersen,K E, PY - 1980/6/1/pubmed PY - 1980/6/1/medline PY - 1980/6/1/entrez SP - 155 EP - 62 JF - Acta pathologica et microbiologica Scandinavica. Section C, Immunology JO - Acta Pathol Microbiol Scand C VL - 88 IS - 3 N2 - A total of 1223 serum specimens were obtained from 649 consecutive patients attending a dermatovenereological out-patient clinic in Copenhagen with a request for venereal disease control. The sera were examined for gonococcal antibodies by both a gonococcal complement fixation test (GCF) and an indirect haemagglutination test using gonococcal pili as antigens (IHA). The diagnosis of current gonococcal infection in 28 per cent of the patients was based on positive culture for Neisseria gonorrhoeae from one or more of the following sites: urethra, rectum and fauces in all patients, and/or cervix in female patients. The specificity, sensitivity and predictive values of positive and negative test results were calculated for the various groups of patients on the assumption that all positive results, both in patients without gonorrhoea but with a previous gonococcal infection and in patients without known current or previous infection, were false positives. The following values were found: Sensitivity: IHA 45-100%, GCF 6-29%. Specificity: IHA 65-89%, GCF 97-100%. Predictive value of positive test result: IHA 43-74%, GCF 69-100%. Predictive value of negative test result: IHA 78-100%, GCF 61-85%. SN - 0304-1328 UR - https://www.unboundmedicine.com/medline/citation/6108675/An_indirect_haemagglutination_test_for_demonstration_of_gonococcal_antibodies_using_gonococcal_pili_as_antigen__II__Serological_investigation_of_patients_attending_a_dermato_venereological_outpatients_clinic_in_Copenhagen_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0304-1328&date=1980&volume=88&issue=3&spage=155 DB - PRIME DP - Unbound Medicine ER -