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Failure of targeted mass treatment to control schistosomiasis.
Lancet. 1981 Jan 03; 1(8210):27-8.Lct

Abstract

An attempt was made to control schistosomiasis mansoni with mass treatment of all subjects excreting more than 100 eggs/g of faeces. No other means of control to reduce transmission were used. A very low dosage of hycanthone (0.75 mg/kg) appeared insufficient to achieve a satisfactory reduction of the worm load. A higher dosage (1.5 mg/kg) resulted in a significant reduction of the egg output. However, reappearance of eggs, probably indicating reinfection, was very rapid. One year after treatment the egg counts were at about two-thirds of the original level again.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

6109059

Citation

Polderman, A M., and J P. Manshande. "Failure of Targeted Mass Treatment to Control Schistosomiasis." Lancet (London, England), vol. 1, no. 8210, 1981, pp. 27-8.
Polderman AM, Manshande JP. Failure of targeted mass treatment to control schistosomiasis. Lancet. 1981;1(8210):27-8.
Polderman, A. M., & Manshande, J. P. (1981). Failure of targeted mass treatment to control schistosomiasis. Lancet (London, England), 1(8210), 27-8.
Polderman AM, Manshande JP. Failure of Targeted Mass Treatment to Control Schistosomiasis. Lancet. 1981 Jan 3;1(8210):27-8. PubMed PMID: 6109059.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Failure of targeted mass treatment to control schistosomiasis. AU - Polderman,A M, AU - Manshande,J P, PY - 1981/1/3/pubmed PY - 1981/1/3/medline PY - 1981/1/3/entrez SP - 27 EP - 8 JF - Lancet (London, England) JO - Lancet VL - 1 IS - 8210 N2 - An attempt was made to control schistosomiasis mansoni with mass treatment of all subjects excreting more than 100 eggs/g of faeces. No other means of control to reduce transmission were used. A very low dosage of hycanthone (0.75 mg/kg) appeared insufficient to achieve a satisfactory reduction of the worm load. A higher dosage (1.5 mg/kg) resulted in a significant reduction of the egg output. However, reappearance of eggs, probably indicating reinfection, was very rapid. One year after treatment the egg counts were at about two-thirds of the original level again. SN - 0140-6736 UR - https://www.unboundmedicine.com/medline/citation/6109059/Failure_of_targeted_mass_treatment_to_control_schistosomiasis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0140-6736(81)90127-6 DB - PRIME DP - Unbound Medicine ER -