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Drug combinations in the treatment of refractory depression: a review.
J Clin Psychiatry. 1981 Oct; 42(10):368-73.JC

Abstract

The authors critically review several drug combinations that may be of promise in the management of depressions that do not respond to treatment with a single drug. These include the use of tricyclic antidepressants with monoamine oxidase inhibitors (MAOI's), L-triiodothyronine (T3), methylphenidate, lithium carbonate, L-tryptophan, reserpine, and neuroleptics; MAOI's with lithium and L-tryptophan; and L-tryptophan with allopurinol. The authors stress the need for further double-blind, controlled studies to evaluate the safety and efficacy of these combinations.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.
Review

Language

eng

PubMed ID

6116699

Citation

Stern, S L., and J Mendels. "Drug Combinations in the Treatment of Refractory Depression: a Review." The Journal of Clinical Psychiatry, vol. 42, no. 10, 1981, pp. 368-73.
Stern SL, Mendels J. Drug combinations in the treatment of refractory depression: a review. J Clin Psychiatry. 1981;42(10):368-73.
Stern, S. L., & Mendels, J. (1981). Drug combinations in the treatment of refractory depression: a review. The Journal of Clinical Psychiatry, 42(10), 368-73.
Stern SL, Mendels J. Drug Combinations in the Treatment of Refractory Depression: a Review. J Clin Psychiatry. 1981;42(10):368-73. PubMed PMID: 6116699.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Drug combinations in the treatment of refractory depression: a review. AU - Stern,S L, AU - Mendels,J, PY - 1981/10/1/pubmed PY - 1981/10/1/medline PY - 1981/10/1/entrez SP - 368 EP - 73 JF - The Journal of clinical psychiatry JO - J Clin Psychiatry VL - 42 IS - 10 N2 - The authors critically review several drug combinations that may be of promise in the management of depressions that do not respond to treatment with a single drug. These include the use of tricyclic antidepressants with monoamine oxidase inhibitors (MAOI's), L-triiodothyronine (T3), methylphenidate, lithium carbonate, L-tryptophan, reserpine, and neuroleptics; MAOI's with lithium and L-tryptophan; and L-tryptophan with allopurinol. The authors stress the need for further double-blind, controlled studies to evaluate the safety and efficacy of these combinations. SN - 0160-6689 UR - https://www.unboundmedicine.com/medline/citation/6116699/Drug_combinations_in_the_treatment_of_refractory_depression:_a_review_ L2 - http://www.diseaseinfosearch.org/result/2199 DB - PRIME DP - Unbound Medicine ER -